BACKGROUND Determination of oocyte fertilization and embryo quality are one of the most important purposes in ART cycles. Follicular fluid provides an important microenvironment for development of oocytes and some biochemical characteristics of the follicular fluid, such as pregnancy-associated plasma protein-A (PAPP-A), may play an important role in prediction of success rate of ART. OBJECTI...

Some of the major serum proteins that are also found in follicular fluid, including transferrin, alpha-macroglobulin and albumin, are thought to play a role in oocyte maturation. This study set out to identify proteins in human follicular fluid by capillary zone electrophoresis and to investigate their relationship to follicular/oocyte maturity and fertility outcome. 176 individual follicular f...

background: determination of oocyte and embryo quality are one of the most important goals in ivf. anti-mullerian hormone (amh) is secreted by the ovarian granulosa cells into blood flow and follicular fluid. follicular fluid anti-mullerian hormone level is probably a marker of activity of granulose cells. objective: to evaluate whether high level of follicular fluid anti-mullerian hormone leve...

Background: Induction of in vitro maturation and development of immature oocyte is one of the methods that has been frequently used recently in artificial reproduction techniques and has drawn attention of many investigators. This method is useful especially in women who are affected by cancer and polycystic ovary syndrome. Despite using many types of in vitro media, an appropriate environment ...

Background: Recent studies have revealed that adiponectin, a novel adipocytokine, and its two receptors (AdipoR1 and AdipoR2) are involved in regulation of ovarian function in various farm animal species. The aim of this study was to investigate the gene expression pattern of Adiponectin and its receptors in ovarian cells of dominant (DFs) and non- dominant follicles (NDFs) in the bovine. Mater...

The follicular fluid environment surrounding the oocytes may play a critical role in fertilization and subsequent embryo development. The goal of our study was to evaluate the oxidative stress markers in the semen, blood serum, and follicular fluid of couples undergoing Intracytoplasmic Sperm Injection (ICSI). Two hundred and eight infertile couples underwent ICSI and the levels of superoxide d...

Maternal heat stress reduces oocyte competence for fertilization and post-fertilization development, but the mechanism is unknown. The present experiment investigated two potential mechanisms: (1) reduced oxygen delivery to the preovulatory follicle (due to increased thermoregulatory vascular perfusion of skin and respiratory tract); (2) reduced follicular steroid synthesis. These hypotheses we...

Background: Polycystic ovary syndrome (PCOS) is a common cause of infertility often responsive to treatment with oral ovulation induction agents. PCOS patients are typically characterized by producing an increased number of oocytes that they are often of poor quality, leading to lower fertilization, cleavage and implantation rates. Recently data involve functional associations between endocrine...