background: the differential efficacy between long gnrh agonist with antagonist can partly be due to the preexisting differences in the early antral follicles before ovarian stimulation. objective: to compare the effect of pretreatment by estradiol with gnrh antagonist on antral follicular size coordination and basal hormone levels in gnrh antagonist protocol. materials and methods: on cycle da...

background: the retrieval of good quality oocytes that is accomplished with selection of the best induction ovulation protocol on the basis of patients condition, age and cause of infertility, is one of the most important aspects of art cycles. the objective was to evaluate the efficacy of low dose, long acting gnrh-a (decapeptyle) for pituitary desensitization and outcome of art compared to lo...

OBJECTIVE To compare the two GnRH-a protocols (long GnRH-a protocol and short GnRH-a protocol) for ovarian stimulation in IVF/ICSI cycles in patients of various age ranges. METHODS A total of 5662 IVF-ET/ICSI cycles from 2010 to 2013 were retrospectively identified. The cycles were divided into two groups: a long protocol group and short protocol group. In each group, the patients were divide...

BACKGROUND Women with polycystic ovary syndrome (PCOS) are at risk of developing ovarian hyperstimulation syndrome (OHSS) during ovarian stimulation. Use of GnRH antagonist in the general subfertile population is associated with lower incidence of OHSS than agonists and similar probability of live birth but it is unclear if this is true for patients with PCOS. Our aim was to compare the flexibl...

Suppression of endogenous hormone production by gonadotrophin-releasing hormone (GnRH) agonists followed by controlled ovarian hyperstimulation (COH) with human gonadotrophins, especially the so-called 'long protocol' has developed from second-line into first-line therapy. Due to this attitude premature luteinization can be safely avoided, enhancing therapeutic efficacy. Recombinant preparation...

BACKGROUND GnRH agonist and antagonist were developed to control the premature release of LH surge. There is some difference between two protocols. OBJECTIVE We compared the outcome of frozen-thawed embryo transfer in infertile women who used GnRH agonist or antagonist protocol for previous COH cycle and evaluation of any adverse effect of GnRH antagonist on oocyte and embryo. MATERIALS AND...

BACKGROUND GnRH agonist was recently suggested as a novel luteal-phase support that may act at different levels, including the pituitary gonadotrophs, the endometrium and the embryo itself. This prospective randomized study evaluates the effect of GnRH agonist administered in the luteal phase on ICSI outcomes in both GnRH agonist- and GnRH antagonist-treated ovarian stimulation protocols. MET...

background: premature luteinization during in vitro fertilization was commonly happened before the introduction of gnrh analogues. high level of unwanted progesterone is associated with adverse pregnancy outcome and is thought to be induced by inappropriate lh elevation.objective: to evaluate the progesterone level on the day of human chorionic gonadotropin (hcg) triggering in gnrh agonist and ...

Background: This study aims to verify if luteal estradiol pre-treatment improves IVF/ICSI outcomes in a GnRH antagonist protocol as compared to a micro dose GnRH agonist protocol in poor-responding patients. Materials and Methods: A total of 116 IVF/ICSI cycles were included in this prospective randomized clinical trial. The selected women were randomly assigned to receive an estradiol pre-trea...