BACKGROUND The Global Mood Scale (GMS; [Denollet, J., 1993a. Emotional distress and fatigue in coronary heart disease: the Global Mood Scale (GMS). Psychol Med 23, 111-121., Denollet, J., 1993b. The sensitivity of outcome assessment in cardiac rehabilitation. J Consult Clin Psychol 61, 686-695.]) was originally developed as a measure of positive affect (PA) and negative affect (NA) in cardiac p...

BACKGROUND Whether long-chain polyunsaturated fatty acids (LCPs) play a role in the development of the young nervous system in term infants is debated. OBJECTIVE We investigated whether supplementation of formula with LCPs for 2 mo improves the quality of general movements (GMs) in healthy term infants at 3 mo of age. DESIGN A prospective, double-blind, randomized controlled study was condu...

Materials Sodium form of hyaluronic acid (HA, MW, 10 kDa) was a gift of Kolon Life Science, Korea. EDC.HCl (99%) and N-Hydroxy succinimide (NHS, 99%) were purchased from Shanghai Medeep Co., Ltd. Monostearin (glycerol α-monostearate, GMS), Sodium deoxycholate (DOC) and fluorescein isothiocyanate (FITC) were purchased from Solarbio (Beijing, China). Doxorubicin hydrochloride (DOX) was supplied b...

BACKGROUND Aortic valve disease is associated with eccentric or concentric left ventricular (LV) hypertrophy and changes in the LV mass. The relationship between LV mass and function and the effect of LV remodeling after aortic valve replacement (AVR), in patients with aortic valve disease needs evaluation, that is largely unknown in our population. The aim of this study was to evaluate the eff...

Sir Dr. Iona Heath, former President of the Royal College of General Practitioners, asked the medical profession to rise to the “challenge of multimorbidity” 1 . Heath argued for the “necessary paradigm shift from a disease based model of care to one that focuses on care for patients” and to move away from single-disease focused guidelines, which silo patients inappropriately. Multimorb...

Genomic mismatch scanning (GMS) is a high-throughput, high-resolution identity by descent mapping technique that enriches for genomic DNA fragments that are shared between related individuals. In GMS, DNA heteroduplexes are formed from restriction-digested genomic DNA fragments from two relatives. Mismatch-free DNA heteroduplexes, likely representing DNA shared identical by descent between the ...

Genomic mismatch scanning (GMS) is a new method of genetic mapping which attempts to purify and map the regions of identity between two complex genomes in a single test. Identical DNA fragments from two genomic sources are enriched in two steps: (i) after reannealing of the two genomes, heterohybrids are purified by using a combination of a restriction methylase and methylation-sensitive endonu...

Recent advances in I/O bus structures (e.g., PCI), highspeed networks, and fast, cheap disks have significantly expanded the I/O capacity of desktop-class systems. This paper describes a messaging system designed to deliver the potential of these advances for network storage systems including cluster file systems and network memory. We describe gms net, an RPClike kernel-kernel messaging system...

The benefits of Markov-based predictive prefetching have been largely overshadowed by the overhead required to produce high quality predictions. While both theoretical and simulation results for prediction algorithms appear promising, substantial limitations exist in practice. This outcome can be partially attributed to the fact that practical implementations ultimately make compromises in orde...