The compositional analyses and safety assessment of glyphosate-tolerant soybeans (GTS) were previously described. These analyses were extensive and included addressing the potential effects on seed composition from the genetic modification. Detailed compositional analyses established that GTS, which had not been treated with glyphosate, were comparable to the parental soybean line and to other ...

Evolutionary biologists explain the maintenance of intermediate levels of defense in plant populations as being due to trade-offs, or negative genetic covariances among ecologically important traits. Attempts at detecting trade-offs as constraints on the evolution of defense have not always been successful, leading some to conclude that such trade-offs rarely explain current levels of defense i...

Transgenic glyphosate-tolerant plants overproducing EPSPS (5-enolpyruvylshikimate-3-phosphate synthase) may exhibit enhanced fitness in glyphosate-free environments. If so, introgression of transgenes overexpressing EPSPS into wild relative species may lead to increased competitiveness of crop-wild hybrids, resulting in unpredicted environmental impact. Assessing fitness effects of transgenes o...

Presence of antibiotic resistance markers has always been considered as one of the main safety concerns in transgenic plants and their derived products. Elimination of antibiotic selectable markers from transgenics is a major hurdle for finding efficient and safe candidates. Herbicide tolerance genes might be attractive alternatives. In this study, a variant form of the 5-enoylpyruvyl shikimate...

The short-term effects of the herbicide glyphosate (1.25-10 mM) on the growth, nitrogen fixation, carbohydrate metabolism, and shikimate pathway were investigated in leaves and nodules of nodulated lupine plants. All glyphosate treatments decreased nitrogenase activity rapidly (24 h) after application, even at the lowest and sublethal dose used (1.25 mM). This early effect on nitrogenase could ...

Crops engineered to contain genes for tolerance to multiple herbicides may be treated with several herbicides to manage weeds resistant to each herbicide. Thus, nearby non-target plants may be subjected to increased exposure to several herbicides used in combination. Of particular concern are native plants, as well as adjacent crops which have not been genetically engineered for tolerance to he...

In many crops, weeds are managed by herbicides, mainly due to the decrease in crop yields and farmers’ incomes caused by them. In general, chemical control of weeds is considered to be an easy, relatively cheap, and highly effective method. However, not all weeds can be successfully controlled, either because of their natural tolerance or their herbicide resistance. Glyphosate is one of the mos...

Glyphosate has been used globally as a safe herbicide for weed control. It inhibits 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase (AroA), which is a key enzyme in the aromatic amino acid biosynthetic pathway in microorganisms and plants. A Pseudomonas putida strain, 4G-1, was isolated from a soil heavily contaminated by glyphosate in China. Its AroA-encoding gene (aroA) has been cloned, se...

presence of antibiotic resistance markers has always been considered as one of the main safety concerns in transgenic plants and their derived products. elimination of antibiotic selectable markers from transgenics is a major hurdle for finding efficient and safe candidates. herbicide tolerance genes might be attractive alternatives. in this study, a variant form of the 5-enoylpyruvyl shikimate...