BACKGROUND Certain types of carbohydrates increase glucose and insulin levels to a greater extent than others. In turn, insulin may raise levels of insulin-like growth factors, which may influence breast cancer risk. We analyzed the effect of type and amount of carbohydrates on breast cancer risk, using the glycemic index and the glycemic load measures in a large case-control study conducted in...

OBJECTIVE We studied the association of digestible carbohydrates, fiber intake, glycemic index, and glycemic load with insulin sensitivity (S(I)), fasting insulin, acute insulin response (AIR), disposition index, BMI, and waist circumference. RESEARCH DESIGN AND METHODS Data on 979 adults with normal (67%) and impaired (33%) glucose tolerance from the Insulin Resistance Atherosclerosis Study ...

L ifestyle changes, in particular reducing energy intake, are the cornerstone of current approaches to weight loss and prevention of type 2 diabetes. However, there is currently no consensus that one dietary regimen is more effective than another for weight loss (1) or whether particular diets work better for identifiable groups of individuals. There is evidence, however, to suggest that both i...

Bu derleme yazıda glisemik indeks ve yükün kanser gelişimi üzerindeki potansiyel etkilerinin incelenmesi hedeflenmiştir. Glisemik ve/veya yük değeri yüksek olan besinlerin; glukoz metabolizmasını etkileyerek ileri glikasyon son ürünlerinin oluşmasına, disbiyoz gelişmesine, insülin benzeri büyüme faktörü (insulin like growth factor, IGF) aracılığı ile hücre çoğalmasına Deoksiribo Nükleik Asit (D...

BACKGROUND The influence of glycemic load and related measures on survival among colon cancer patients remains largely unknown. METHODS We conducted a prospective, observational study of 1011 stage III colon cancer patients reporting dietary intake during and 6 months after participation in an adjuvant chemotherapy trial. We examined the influence of glycemic load, glycemic index, fructose, a...

In this issue of Diabetes Care, Liese et al. (1) report on the relation of dietary glycemic index, glycemic load, carbohydrate, and fiber intake to measures of insulin sensitivity, insulin secretion, and adiposity in the Insulin Resistance Atherosclerosis Study (IRAS). The evaluation was confined to those with normal or impaired glucose tolerance and did not include diabetic individuals. As the...