Several studies have shown that stress has major effects on metabolism. There is also some evidence indicating that stress may induce diabetes mellitus. The present study has investigated the role of chronic psychological stress on carbohydrate metabolism in male Wistar rats (250 ± 50 g). Animals were divided into control and test groups (n = 8/group). Blood samples were obtained by tail snippi...

Background: Environmental pollutants including organophosphate insecticides impair glucose metabolism by altering hepatic oxidation and play an important role in the development of diabetes and its complications. The aim of this study was to assess the impacts of repeated oral doses of Diazinon, an organophosphate insecticide, which is known to impair the glucose metabolism and its tolerance th...

background glucose is an essential element in the supply of body’s energy. in diseases such as diabetes, glucose increase is associated with disturbance in metabolism. cortisol is an important hormone in the regulation of glucose metabolism, and human serum albumin (hsa) is one of the most important glucose and cortisol transmitters in blood. interaction between albumin and these ligands could ...

Obesity and insulin resistance are associated with altered brain glucose metabolism. Here, we studied brain glucose metabolism in 22 morbidly obese patients before and 6 months after bariatric surgery. Seven healthy subjects served as control subjects. Brain glucose metabolism was measured twice per imaging session: with and without insulin stimulation (hyperinsulinemic-euglycemic clamp) using ...

Diabetes mellitus, pathoglycemia, dyslipidemia, non-alcoholic fatty liver, overweight, hypertension, and atherosclerosis are common diseases endangering human health. Cachexia is a life-threatening disease condition. associated with increased mortality. Cancer patients cachexia less tolerant have decreased response to chemotherapy radiation. Do these pathogenesis? We will discuss the commonalit...

Metabolic disorders are complex abnormalities involving impaired glucose and lipid metabolism, associated with complications such as kidney disease, cardiovascular foot ulcer, retinopathy, neuropathy [...]

Betatrophin is a member of the angiopoietin-like (ANGPTL) family that has been implicated in both triglyceride and glucose metabolism. The physiological functions and molecular targets of this protein remain largely unknown; hence, a purified available protein would aid study of the exact role of betatrophin in lipid or glucose metabolism. In this study, we cloned the full-length cDNA of betatr...

Background and aims: Alterations in carbohydrate metabolism are frequently observed in cirrhosis; to determine the frequency of diabetes mellitus and impaired glucose tolerance in Tunisian cirrhotic patients and identify risk factors. Patients and methods: Cross-sectional study; fasting plasma glucose levels were measured in consecutive patients with cirrhosis. Oral glucose tolerance test was p...

Prenatal androgen exposure induces metabolic disorders in female offspring. However, the long-term effect of maternal testosterone excess on glucose metabolism, especially pancreatic beta-cell function, is rarely investigated. Our current study mainly focused effects prenatal metabolism and beta- cell function aged By using mice their offspring as animal models, we found that treatment induced ...