strychnos henningsii gilg is recommended among other remedies for the treatment of diabetes in traditional medicine of southern africa. the antidiabetic effect of oral administration of aqueous bark extract of the plant at 125, 250 and 500 mg/kg body weight was investigated in diabetic rats induced with streptozotocin-nicotinamide for 15 days. the extract decreased the blood glucose level, feed...

introduction: current study examined the possible role of the central nucleus of amygdala (cea) transient inactivation on the metabolic and hormonal disturbances induced by acute electro foot shock stress in female rats. considering the differences between female and male in responses to stress, this study attempts to reveal possible mechanisms underlying these differences. methods: uni- or bil...

To test the hypothesis that glucose supply to the uteroplacenta (UP) regulates UP glucose metabolism into oxidative and nonoxidative pathways, we studied eight late-gestation pregnant sheep at low (LG) and high (HG) maternal glucose concentrations (GM), using Fick principle and tracer glucose methodology. UP glucose consumption (UPGC) correlated directly with GM( r = 0.75, P = 0.0006), and UP g...

glucose and insulin are two important factors in regulation of food intake. also, existence of central glucoreceptors have been determined in human and many of  animal species, in this study the existence of central glucoreceptors and regulative role of glucose in ingestive behavior of broiler cockerels were studied. in this study used from 128 broiler cockerels. at the first, guide cannula imp...

objective: stress and cortisol increase blood glucose. considering the role of central catecholaminergic pathways on hypothalamic-pituitary adrenocortical axis, and results of some studies that alprazolam (a benzodiazepine) has inhibitory effect on catecholamines, it seems that alprazolam may reduce blood glucose. the aim of this study was to evaluate the effect of alprazolam on serum insulin l...

objective: as the aqueous extract of capparis spinosa (cs) possess antidiabetic effect, he present study aims to reveal the possible  mechanism of action of cs in diabetic mice.materials and methods: both single and repeated oral administrations of aqueous extract of cs were performed in multi-low dose streptozotocin-induced (mlds) diabetic mice. euglycemic hyperinsulinemic clamp was used in as...

objective: social belief and experimental evidences indicate that opium and its alkaloids, morphine, produced hypoglycemic effects in animal models. this study was conducted in order to determine the role of morphine on blood glucose and insulin. material and methods: this is an empirical analysis investigating the laboratory albino male rats weighing 200-250 g. rats in the control group receiv...