In this paper, we compare two implementations of a grid-based software system on the grid middleware Globus Toolkit 4 and gLite, respectively. This system called “Grid-Enabled SEE++” is a grid-based simulation software that supports the diagnosis and treatment of certain eye motility disorders (strabismus). First, we developed a parallel version of the software with the help of Globus 4. Since ...

Deep brain stimulation (DBS) therapy has become an essential tool for treating a range of brain disorders. In the resting state, DBS is known to regularize spike activity in and downstream of the stimulated brain target, which in turn has been hypothesized to create informational lesions. Here, we specifically test this hypothesis using repetitive joint articulations in two non-human Primates w...

We have evaluated the feasibility of using four positron emission tomography (PET) tracers for imaging the globus pallidus by ex vivo autoradiography in rats. The tracers investigated were [11C]KF18446, [11C]SCH 23390 and [11C]raclopride for mapping adenosine A2A, dopamine D1 and dopamine D2 receptors, respectively, and [18F]FDG. The highest uptake by the globus pallidus was found for [11C]SCH ...

In this paper, we compare two implementations of a grid-based software system on the grid middleware Globus Toolkit 4 and gLite, respectively. This system called “Grid-Enabled SEE++” is a grid-based simulation software that supports the diagnosis and treatment of certain eye motility disorders (strabismus). First, we developed a parallel version of the software with the help of Globus 4. Since ...

The globus pallidus plays a critical role in movement regulation. Morphological study has indicated that the globus pallidus receives neurotensinergic innervation from the striatum. The present study investigated the effects of activating neurotensin receptor in globus pallidus. In vivo single unit electrophysiological recordings showed that micro-pressure ejection of neurotensin into the globu...

The Globus project is a multi-institutional research effort that seeks to enable the construction of computational grids providing pervasive, dependable, and consistent access to high-performance computational resources, despite geographical distribution of both resources and users. Computational grid technology is being viewed as a critical element of future highperformance computing environme...

"Globus sensation" is often described as the sensation of a lump in the throat associated with dry swallowing or the need for dry swallowing, which disappears completely during eating or drinking and for which no organic cause can be established. Due to the uncertain etiology of "globus sensation", it remains difficult to establish standard treatment strategies for affected patients. Lately mos...

We propose that research data management capabilities be delivered to users as hosted “software as a service” (SaaS). We report on a system, Globus Online, that adopts this approach, initially for a small set of data movement functions. Globus Online leverages modern Web 2.0 technologies to provide fire-and-forget file transfers, automatic fault recovery, and high performance, while also simpli...

Iontophoretic injections of the fluorescent retrograde tract tracer, Fluoro-gold, into the entopeduncular nucleus of the rat (homologous to the internal segment of the primate globus pallidus) resulted in a substantial number of retrogradely labeled neurons in the ipsilateral globus pallidus (homologous to the external segment of the primate globus pallidus). In experiments confirming this proj...

The need for organisations to share data and collaborate on a large scale with geographically dispersed parties has increased dramatically in recent years. Grid Services allow for large scale collaboration between geographically-dispersed parties running diverse hardware and software platforms, over public networks such as the Internet. Grid Services are an evolution of Web Service technology a...