introduction: over the past two decades, the incidence of cesarean section in most countries has increased.developmental delay occurs when children do not reach their developmental milestones at the expected time. the main causes of developmental delay are often unknown. investigation of the prevalence of developmental delay and its effective factors in children from 4 to 12 months old in pakda...

how to cite this article: yaghini o, danesh f, mahmoudian t, beigi b. evaluation of developmental delay in infants who came in for 6th month vaccination in isfahan city health centers. iran j child neurol 2012;6(2): 29-32.   objective developmental delay is one of the most common causes of conferring the pediatric neurologist. the main part of neurological growth and development occur in the fi...

INTRODUCTION The 22q13.3 deletion syndrome (MIM 606232) is characterised by neonatal hypotonia, normal to accelerated growth, absent to severely delayed speech, global developmental delay, and minor dysmorphic facial features. We report the molecular characterisation of the deletion breakpoint in two unrelated chromosome 22q13.3 deletion cases. METHODS The deletions were characterised by FISH...

This study reports on two individuals with Temple-Baraitser syndrome, manifesting typical hallux and pollex findings, global developmental delay, and seizures. In the five previous cases identified to date, consistent craniofacial and osseous characteristics have been observed. The children described herein exhibit minor differences within this phenotype and are older, highlighting the phenotyp...

BACKGROUND Investigation of patients, particularly children, with unexplained global developmental delay (GDD)/learning disability (LD) has been challenging due to a lack of clear guidance from specialised centres. Limited knowledge of rare diseases and a poor understanding of the purpose or limitations of appropriate investigations have been some of the principal reasons for this difficulty. ...

Earliest identifiable findings in autism indicate that the autistic brain develops differently from the typical brain in the first year of life, after a period of typical development. Twin studies suggest that autism has an environmental component contributing to causation. Increased availability of audiovisual (AV) materials and viewing practices of infants parallel the time frame of the rise ...

how to cite this article: firoozeh sajedi f, ahmadi doulabi m, vameghi r, mazaheri ma, akbarzadeh baghban ar. relationship of mothers’ psychological status with development of kindergarten children. iran j child neurol. summer 2016; 10(3):61-72.   abstract objective given the importance of children’s development and the role of psychological status of mothers in this regard, this study investig...

Dr. Jones is a gynecologist who has been seeing Amy for the past few years to help with menstrual suppression. Amy was diagnosed with cerebral palsy at birth; she experienced some global developmental delay as a child and was in special education in school. Now 25, Amy works part-time at a local grocery store. Amy’s mother currently holds her medical power of attorney, but she makes a concerted...

Mutations in the human N-glycanase 1 (NGLY1) cause a rare, multisystem congenital disorder with global developmental delay. However, the mechanisms by which NGLY1 and its homologs regulate embryonic development are not known. Here we show that Drosophila Pngl encodes an N-glycanase and exhibits a high degree of functional conservation with human NGLY1. Loss of Pngl results in developmental midg...

Global developmental delay (GDD) is a chronic neurological disturbance which includes defects in one or more developmental domains. The developmental domain can be motor, cognitive, daily activities, speech or language, and social or personal development. The etiology for GDD can be prenatal, perinatal, or postnatal. It can be diagnosed early in childhood as the delay or absence of one or more ...