Gingerols, the pungent ingredients in ginger, are reported to possess a cholesterol-lowering activity. However, the underlying mechanism remains unclear. The present study was to investigate how 6-gingerol (6-GN), the most abundant gingerol in fresh ginger, regulates hepatic cholesterol metabolism. HepG2 cells were incubated with various concentrations of 6-GN ranging from 50 to 200 μM for 24 h...

This study sought to determine the utility of liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) coupled with diode array detection in identifying gingerol-related compounds from crude extracts of ginger rhizome. The fragmentation behaviors of compounds in both (-)- and (+)ESI-MS/MS were used to infer and confirm the chemical structures of several groups of co...

Ginger (Zingiber officinale) is a common kitchen spice that belongs to the family Zingiberaceae. It rich in phytochemistry promoting health benefits. used as home remedy support cold, headaches, and pharmacological properties such anti-inflammatory, antioxidant, antiemetic, antiulcer, anti-cancer, antiplatelet, anti-diabetic lipid-lowering activities. Gingerols are key ingredients found ginger ...

The rapid increase in agricultural waste is rising across the globe and a big environmental challenge. utilization of ginger as valuable product very limited. up-cycling an effective approach for valorization. Ginger contains many bio-active compounds. These bioactive compounds possess various functional properties. literature has indicated that its rich source shogaol zingerone gingerols, thes...

Ginger is a flowering plant in the Zingiberaceae family (Zingiber officinale Roscoe). The most essential ingredient our meal ginger, which utilized as spice. One of earliest recognized medicinal herbs, ginger has been used for centuries to treat variety human diseases. Sesquiterpenoids, monoterpenoids, volatile oils (1–5%), and non-volatile pungent chemicals such gingerols, shogaols, paradols, ...

In this study we investigate the active constituents of the rhizome of Zingiber officinale, Roscoe (ginger) and determine their activity on glucose uptake in cultured L6 myotubes and the molecular mechanism underlying this action. Freeze-dried ginger powder was extracted with ethyl acetate (1 kg/3 L) to give the total ginger extract, which was then separated into seven fractions, consisting of ...

Daikenchuto (DKT), a pharmaceutical-grade traditional Japanese (Kampo) medicine, has been widely used for the treatment of various gastrointestinal disorders including postoperative ileus and has been integrated into the modern medical care system in Japan as a prescription drug. DKT is a multiherbal medicine consisting of Japanese pepper (zanthoxylum fruit), processed ginger, and ginseng with ...

Abstract Objectives Dried ginger and are the same type of medicine food. The differential components dried ginger, charcoal were investigated. Materials Methods experimental materials divided into three sample groups: group, group. group qualitatively analyzed by ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry. data processed Marker View Software...