OBJECTIVE To evaluate the impact of brief and sequential exposure to nystatin on the germ tube formation and cell surface hydrophobicity of oral isolates of Candida albicans obtained from patients infected with human immunodeficiency virus (HIV). MATERIALS AND METHODS After determining the minimum inhibitory concentration of nystatin, 10 oral isolates of C. albicans from 10 different HIV-infe...

OBJECTIVE Candida-associated denture stomatitis is a very common disease affecting denture wearers. It is characterized by the presence of yeast biofilm on the denture, primarily associated with C. albicans. The investigation of agents that can reduce C. albicans adhesion may represent a significant advancement in the prevention and treatment of this disease. This study aims to investigate the ...

Candida albicans is often isolated from clinical samples, thus its presumptive differentiation from other species of the same genus can be based on its ability to form the germ tube in human serum. Nevertheless, there are two other species that share this characteristic: C. dubliniensis and C. africana. The aim of this study was to compare four different substrates to perform the germ tube (GT)...

Candida albicans has three genes encoding chitin synthase enzymes. In wild-type strains, the expression of CHS2 and CHS3 peaked 1-2 h after the induction of hyphal growth, whilst mRNA levels in a non-germinative strain, CA2, remained low under the same conditions. CHS1 gene expression did not peak during germ tube formation but remained at low levels in both yeast and hyphal growth. The pattern...

Introduction: The opportunistic fungus Candida albicans is a normal flora of human. Due to the increase in the number of immunocompromised patients, infections due to the Candida species have considerably increased in the resent years. Extracellular hydrolytic enzymes appear to play an essential role in candidal overgrowth. Dimorphism, adhesions, and the production of hydrolytic enzymes are sug...

Background: Candida albicans is a common pathogenic, and the germ tube test one of identification techniques for this fungal species. Objectives: 1. To experiment with C. in various media according to different testing time. 2. evaluate capacity ofthe media. Methods: This study was carried out 36 isolates 10 tropicalis stored at Department Parasitology. Germ performed using media, including hum...

Objective: To determine the efficacy of direct germ tube method in early detections of candida albicans. Introduction: Blood stream infections (BSIs) caused by Candida species are on the increase and associated with high mortality rates, which are due in part to delay in the administration of appropriate antifungal therapy. Earlier identification of yeast isolates from blood cultures may improv...

Background and Purpose: Ozone is an inorganic molecule with effective antimicrobial properties. Clinical treatment of ozonated water was used for the elimination of Candida albicans, Enterococcus faecalis, endotoxins, and biofilms from root canals. In addition, its therapeutic effects for tinea pedis, ulcers, and leishmaniasis were investigated. The purpose of the present study was to evaluate ...

Hydrophobic interaction is generally considered to play an important role in the adherence of microorganisms to eukaryotic cells and also to certain inert surfaces. Using a microbe adhesion assay to hydrocarbons (n-hexadecane), 68 strains of Candida albicans and 30 non-albicans strains were studied. Influence of source of isolate, age of the culture, and percentage of germ tube formation on adh...