The concurrent use of drugs and herbal products is becoming increasingly prevalent over the last decade. Several herbal products have been known to modulate cytochrome P450 (CYP) enzymes and P-glycoprotein (P-gp) which are recognized as representative drug metabolizing enzymes and drug transporter, respectively. Thus, a summary of knowledge on the modulation of CYP and P-gp by commonly used her...

fire is one of the incorporate vegetation management practices for grasslands and semi-arid rangelands. it may affect symbiotic relationship between range plants and mycorrhiza. accordingly, this research was aimed to investigate the effects of a spring prescribed fire on the symbiotic relationships between mycorrhiza and 6 plant species. the study was conducted in a semi-arid steppe rangeland ...

the primary aim of plant breeding is to improve stability in yield and to obtain varieties with good quality. for this reason, a study of wheat varieties was conducted in 2010, 2011, and 2012 at the agricultural application and research center fields of the uludag university, agricultural faculty, in bursa/turkey. in the study, 22 advanced lines of bread wheat and gonen, pehlivan, and flamura c...

drug interaction may cause sever adverse drug reactions in patients. the high amounts of prescribed medication in hospitalized patients will cause higher incidence of drug interactions. therefore, the study of drug interactions in hospitalized patients seems to be worth. we have, studied drug interaction in internal and surgical units, in kashani hospital in shahrekord. factors included in this...

Background: Protein-protein interactions do not provide any direct information re‌garding the domains within the proteins that mediate the interactions. The majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. Most of the former studies focus only on interacting do‌main pairs. However they do not consider the in...

objective: to evaluate the effect of niprd-am1 on cyp3a4 in order to generate clinically significant data for its safe and efficacious use. materials and methods: niprd-am1 is a phytomedicine developed from aqueous root extracts of nauclea latifolia smith (rubiaceae) for the treatment of uncomplicated malaria. the effect of niprd-am1 on cyp3a4 was measured with and without the addition of niprd...

this study demonstrates the spectral data for two triarylmethane dyes, malachite green (mg) and crystal violet (cv) at room temperature. effects of micellar environment, and crown ether addition on the spectral behaviour of the dyes were studied using absorption spectroscopic method. the dye-anionic surfactant interactions in micellar media were investigated. the chosen surfactants with differe...

the density and viscosity values at t= (293.15 to 323.15) k for binary mixtures of nitromethane with 2-propanol, 2-butanol and 2-pentanol were measured over the entire composition range. from the experimental data, excess molar volumes, thermal expansion coefficients, excess thermal expansions, partial molar volumes at infinite dilution and deviations in viscosity were calculated. the results w...