background and objective: over the recent years, genetically modified food in varieties of corn, soybeans, canola and cotton have been introduced to the global market. this study reviews the health and nutritional value of genetically modified foods in the past two decades. results and conclusions: contrary to the present biotechnological claims, transgenic products did not prove to be so flawl...

Based on a bibliographic review, the article identifies and offers a critical analysis of scientific production by the public health field in Brazil on genetically modified organisms and food (in)security. Of the 716 articles found on the portals of the Scientific Electronic Library Online (SciELO) and the Coordinating Agency for the Development of Higher Education (Capes), only 8 address the f...

The aim of this research is to systematize scientific data on the pharmacokinetics and pharmacogenetics macrolides. Macrolides are a class broad-spectrum antibiotics used treat wide range both topical systemic infectious diseases. Despite fact that macrolide use generally considered be safe, in number patients it can associated with dose-dependent adverse drug reactions (ADRs), reducing safety ...

In the present study, we investigated plasma corticosterone levels of genetically modified mice lacking noradrenaline transporter (NET(-/-)), in response to the forced swim test (FST) and tail suspension test (TST). FST strongly increased the plasma corticosterone level in the first minute after the test (significantly only in NET(+/+) mice), while TST was without any significant effect in both...

Recently, apoptosis (genetically programmed cell death) induced by UV has been documented in some cell culture models. However, the significance of apoptosis in UV-induced cytotoxicity and resistance is uncertain. In this study, we investigated the induction of apoptosis in HeLa cells and its role in acquired UV-resistance. The membrane receptor Fas was induced to assembly, and its immediate do...

Dose effects of triethylenemelamine (TEM) in the induction of dominant-lethal mutations were studied at the early spermatozoon, midspermatid and spermatocyte stages. The pattern of effects on spermatocytes, unlike midspermatids and early spermatozoa, indicated possible cytotoxic damage, so for the determination of TEM dose-response curves in the induction of genetic damage only the data for mid...