نتایج جستجو برای: genetic linkage analysis

تعداد نتایج: 3297133  

Journal: :genetics in the 3rd millennium 0
reza darvishzadeh ahmad heidari hamid hatami maleki

potato virus y (pvy) is one of the most important pathogenic agents that reduce the yield and quality of tobacco (nicotiana tabacum l.). dna-based molecular markers are valuable tools for identifying germplasm in gene banks, assessing kinship ties, and doing marker-assisted selection (mas) for resistance to pests, diseases, and some crop traits of interest. this work presents the results of ass...

Journal: :British Journal of Psychiatry 1982

Journal: :iranian journal of basic medical sciences 0
somayeh reiisi department of genetics, faculty of basic sciences, university of shahrekord, shahrekord, iran mohammad amin tabatabaiefar medical genetics dept., isfahan university of medical sciences, medical genetics dept., national institute of genetic engineering and biotechnology (nigeb), isfahan, iran mohammad hosein sanati medical genetics dept., national institute of genetic engineering and biotechnology (nigeb) morteza hashemzadeh chaleshtori cellular and molecular research center, shahrekord university of medical sciences, shahrekord, iran

objective(s): non-syndromic sensorineural hearing loss (nshl) is a common disorder affecting approximately 1 in 500 newborns. this type of hearing loss is extremely heterogeneous and includes over 100 loci. mutations in the gjb2 gene have been implicated in about half of autosomal recessive nshl (arnshl) cases, making this the most common cause of arnshl. for the latter form of deafness, most f...

Journal: :iranian journal of basic medical sciences 0
ezzat dadkhah department of human genetics, immunology research centre, avicenna research institute, mashhad university of medical science, mashhad, iran masood ziaee birjand hepatitis research centre, birjand university of medical sciences, birjand, iran mohammad hossein davari ophthalmology department, vali-e-asr hospital, birjand university of medical sciences, iran toba kazemi birjand atherosclerosis and coronary artery research centre, birjand university of medical sciences, birjand, iran mohammad reza abbaszadegan department of human genetics, immunology research centre, avicenna research institute, mashhad university of medical science, mashhad, iran medical genetic research centre (mgrc), school of medicine, mashhad university of medical sciences, mashhad, iran

objective(s)marfan syndrome (mfs) is a severe connective tissue disorder withan autosomal dominant inheritance pattern. early diagnosis is critical in mfs. because of the large size of fibrillin-1 gene (fbn1), the uniqueness of mutations, and the absence of genotype-to-phenotype correlations linkage analysis can be very helpful for early diagnosis of mfs. in this study, eight polymorphic marker...

Journal: :iranian journal of public health 0
samira asgharzade somayeh reiisi mohammad amin tabatabaiefar morteza hashemzadeh chaleshtori

background: hearing loss (hl) is the most frequent neurosensory impairment. hl is highly heterogeneous defect. this disorder affects 1 out of 500 newborns. this study aimed to determine the role of dfnb2 locus and frequency of myo7a gene mutations in a population from west of iran. methods: thirty families investigated in shahrekord university of medical sciences in 2014, genetic linkage analys...

ژورنال: توانبخشی 2013
Mohseni , Marzieh, A'bedini, Seyyedeh Sedigheh, Arjangi , Sanaz, Bani-Hashemi , Sousan, Behjati, Farkhndeh, Farhadi, Akram, Hosseini, Ma'soumeh, Kahrizi, Kimia, Najm-Abadi, Hossein, Papari, Elaheh,

Objective: About 50% of severe to profound intellectual disabilities (ID) are caused by genetic factors. In this study we decided to investigate the genetic causes of ID in 69 Bushehrian families to provide information for genetic counseling, carrier detection, and prenatal diagnosis. Materials & Methods: In this study we excluded known chromosomal abnormalities. The majority of families had...

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