Objective(s): Leishmaniasis is a complex parasitic disease that represents a major public health problem. Despite numerous attempts over the past decades, yet there is no effective vaccine against human leishmaniasis probably due to the lack of suitable adjuvants. In this study, a first generation liposomal-based Leishmania vaccine was developed using soluble Leishmania major antigens (SLA) and...

Quality-of-service and SLA guarantees are among the major challenges of cloud-based services. In this paper we first present a new cloud model called SLAaaS – SLA aware Service. SLAaaS considers QoS levels and SLA as first class citizens of cloud-based services. This model is orthogonal to other SaaS, PaaS, and IaaS cloud models, and may apply to any of them. More specifically we make three con...

THE SLA (swine leukocyte antigen, MHC: SLA) genes are the most important determinants of immune, infectious disease and vaccine response in pigs; several genetic associations with immunity and swine production traits have been reported. However, most of the current knowledge on SLA is limited to gene coding regions. MicroRNAs (miRNAs) are small molecules that post-transcriptionally regulate the...

OBJECTIVE(S) Soluble Leishmania antigens (SLA) provide suitable protection against leishmaniasis in murine model when delivered by an appropriate delivery system. Liposomes have been shown to be suitable vaccine delivery systems against leishmaniasis, however, the phospholipase-A (PLA) activity of SLA is a drawback to prepare a stable liposomal SLA. One strategy to overcome this problem might b...

The porcine major histocompatibility complex (MHC) is called swine leukocyte antigen (SLA), which controls immune responses and transplantation reactions. The SLA is mapped on pig chromosome 7 (SSC7) near the centromere. In this study, 3 class I (SLA-1, SLA-3, and SLA-2) and 3 class II (DRB1, DQB1, and DQA) genes were used for investigation of SLA haplotypes in Yucatan miniature pigs in Korea. ...

background: heat shock proteins (hsp) are highly conserved molecules with many immunological functions. they are highly immunogenic with important role in cancer immunotherapy and in vaccine development against infectious diseases. as adjuvant, hsp can augment the immunogenicity of weak antigens and can stimulate antigen presenting cells. although vaccines have been successful for many infectio...

In this volume, Tarone, Bigelow, and Hansen identify two gaps in current second language acquisition (SLA) research. First of all, they note that illiterate and low-literate second language (L2) learners are rarely the targets of SLA inquiry and thus have been left out of the SLA database. The authors consider this omission as a problem that abates the power of current SLA theories to the conte...

1. Recent work shows that large leaves tend to require higher biomass investments per unit leaf area than small leaves. As a consequence, specific leaf area (SLA), which is a focus trait for a bulk of physiological and ecological research programs, is dependent on leaf size variation. Here, we address whether size dependency alters the outcome of research dealing with SLA responses to environme...

PURPOSE The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface. METHODS Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluati...

Please cite this article in press as: Q. He Inform. Sci. (2009), doi:10.1016/j.ins.200 In the web services environment, service level agreements (SLA) refers to mutually agreed understandings and expectations between service consumers and providers on the service provision. Although management of SLA is critical to wide adoption of web services technologies in the real world, support for it is ...