نتایج جستجو برای: gene transduction
تعداد نتایج: 1186299 فیلتر نتایج به سال:
In retroviral vector-mediated gene transfer, transduction efficiency can be hampered by inhibitory molecules derived from the culture fluid of virus producer cell lines. To remove these inhibitory molecules to enable better gene transduction, we had previously developed a transduction method using a fibronectin fragment-coated vessel (i.e., the RetroNectin-bound virus transduction method). In t...
Chinese fir (Cunninghamia lanceolata (Lamb.) Hook.) is a major timber conifer species in southern China. In this study, we aimed to capture the rarely advanced phenomenon for selfing and illustrated underlying molecular mechanism, especially hub gene-regulated networks pathways, by global transcriptome analysis assays (RNA-Seq). Self-pollination trials revealed wide variation of effects among ...
interferons (ifns) are a family of small regulatory glycoproteins that play a central role in the defense against viral infections. although ifns have been initially discovered as antiviral factors, today they are known as an integral part of the cytokine network that affect a wide range of biological processes. ifns exert their pleiotropic effects through their multisubunit cell surface recept...
objective: electroporation can be a highly efficient method for introducing the foreign genetic materials into the targeted cells for transient and/or permanent genetic modification. considering the application of this technique as a very efficient method for drug, oligonucleotide, antibody and plasmid delivery for clinical applications and production of transgenic animals, the present study ai...
Plasmids may have unique advantages as a gene delivery system. However, a major obstacle is the low in vivo transduction efficiency. In this study, an electroporation-based gene transduction approach was taken to study the effect of interleukin (IL)-2 or IL-12 gene transduction on the growth of experimental murine tumors. Significant intratumoral gene transduction was achieved by electroporatio...
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