نتایج جستجو برای: gene library

تعداد نتایج: 1247519  

2015
Zhang Li Dong Z. Xin

Existing antivirus technology depends on extracting signatures. They are inefficient on detecting diverse forms of computer viruses, especially new variants and unknown viruses. Inspired by biological immune system, a virus detection model based on artificial immune and key-signatures extraction is proposed. This model adopt TF-IDF Algorithm to extract virus ODNS from virus DNA parts on code le...

Journal: :Genome 2001
Z N Yang X R Ye S Choi J Molina F Moonan R A Wing M L Roose T E Mirkov

The citrus tristeza virus resistance gene (Ctv) is a single dominant gene in Poncirus trifoliata, a sexually compatible relative of citrus. To clone this gene, a bacterial artificial chromosome (BAC) library has been constructed from an individual plant that was homozygous for Ctv. This library contains 45,696 clones with an average insert size of 80 kb, corresponding to 9.6 genome equivalents....

A. Zare Mirakabadi G. Nikbakht M.H. Motedayen M.J. Rasaee

Human snake bitten poisoning is a serious threat in many tropical and subtropical countries such as Iran. The best acceptable treatment of envenomated humans is antivenoms; however they have a series of economic and medical problems and need more improvements. In this study a combinatorial human immunoglobulin gene library against some of Iranian snakes venoms was constructed. Total RNA prepare...

Journal: :Genome research 1997
A D Simmons J Overhauser M Lovett

Chromosome-specific cDNA libraries are new tools for the isolation of genes from specific genomic regions. We have used two YACs than span the approximately 2-Mb cri-du-chat critical region (CDCCR) of chromosome 5p to directly screen a chromosome 5-specific (CH5SP) fetal brain cDNA library. To compare this library with other sources for new gene discovery, the YACs were hybridized to a normaliz...

2017
Traver Hart Amy Hin Yan Tong Katie Chan Jolanda Van Leeuwen Ashwin Seetharaman Michael Aregger Megha Chandrashekhar Nicole Hustedt Sahil Seth Avery Noonan Andrea Habsid Olga Sizova Lyudmila Nedyalkova Ryan Climie Leanne Tworzyanski Keith Lawson Maria Augusta Sartori Sabriyeh Alibeh David Tieu Sanna Masud Patricia Mero Alexander Weiss Kevin R. Brown Matej Usaj Maximilian Billmann Mahfuzur Rahman Michael Constanzo Chad L. Myers Brenda J. Andrews Charles Boone Daniel Durocher Jason Moffat

The adaptation of CRISPR/SpCas9 technology to mammalian cell lines is transforming the study of human functional genomics. Pooled libraries of CRISPR guide RNAs (gRNAs) targeting human protein-coding genes and encoded in viral vectors have been used to systematically create gene knockouts in a variety of human cancer and immortalized cell lines, in an effort to identify whether these knockouts ...

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