Type B gelatin-based engineered nanovectors system (GENS) was developed for systemic gene delivery in the treatment of pancreatic cancer. The surface of thiolated gelatin nanoparticles was modified with epidermal growth factor receptor (EGFR) specific peptide that targets on the EGFR receptor of Panc-1 cells and this system could release the payload under reducing environment, such as high intr...

Gelatin-based multifunctional composite films were prepared by reinforcing various amounts of copper sulfide nanoparticles (CuSNP, 0.0, 0.5, 1.0, and 2.0 wt %), the effect CuSNP on film was evaluated analyzing its physical antibacterial properties. makes a compatible with gelatin. The inclusion significantly enhanced UV blocking, mechanical strength, water vapor barrier properties gelatin film....

Gold-gelatin bionanocomposite films are prepared by the reduction of gold ions by sodium borohydride in an aqueous solution. It is shown that both the solution and the films on glass substrates contain entrapped hydrogen micro- and nanobubbles with diameters in the range of 200 nm-3 μm. The optical properties of gold nanoparticles in the presence of gelatin and hydrogen nanobubbles are measured...

A simple preparation of thermoreversible gelatin-based ferrogels in water provides a constant structure defined by the crosslinking degree for gelatin contents between 6 and 18 wt%. The possibility of varying magnetite nanoparticle concentration between 20 and 70 wt% is also reported. Simulation studies hint at the suitability of collagen to bind iron and hydroxide ions, suggesting that collage...

this paper provides an overview of how the surface properties of ferromagnetic nanoparticles dispersed in fluids is modified by natural and biocompatible polymers. among common magnetic nanoparticles, magnetite (fe3o4) and maghemite (g-fe203) are popular candidates because of their biocompatibility. natural polymeric coating materials are the most commonly used biocompatible magnetic nanopartic...

Gelatin-stabilized copper sulphide nanoparticles with conjugated doxorubicin have been developed for combined photoacoustic imaging, enzyme-responsive drug release and photothermal therapy.

An excellent gene vector is of great importance for the development of the gene therapy. Gelatin–siloxane nanoparticles (GS NPs) with controlled size and surface charge were synthesized through a two-step sol–gel process for gene vector. In order to increase the efficiency of tumour targeting, HIV-derived Tat peptide and TTA1, a kind of modified RNA aptamer, were further grafted onto GS NPs (GS...

The synthesis of copper nanoparticles was carried out with gelatin as a stabilizer by reducing CuSO4.5H2O ions using hydrazine. Ascorbic acid and aqueous NaOH were also used as an antioxidant and pH controller, respectively. The effects of NaOH, hydrazine, and concentration of gelatin as stabilizer were studied. The synthesized copper nanoparticles were characterized by UV-vis spectroscopy, XRD...

Bioadhesive nanoparticles have been proposed as carriers for the oral delivery of poorly available drugs and facilitate the use of this route. This work summarises some experiments describing the bioadhesive potential of Gantrez nanoparticles fluorescently labeled with rhodamine B isothiocyanate. The adhesive potential of Gantrez was found to be stronger when folded as nanoparticles than in the...

We have fabricated planar structures of silver nanoparticles in monochromatic gelatin emulsion with a continuous spacing ranging from 0.15-0.40 micron using a two-beam interference of a single laser source. Our planar holograms display a colorful "rainbow" pattern and photonic bandgaps covering the visible and IR ranges. We model the planar silver nanoparticle-gelatin composite system using an ...