OBJECTIVES Severe asthma is found in approximately 10% of patients with asthma. Some factors associated with worse asthma control include rhinitis, gastroesophageal reflux disease, vocal cord dysfunction (VCD), nasal polyposis and bronchiectasis. Therefore, we evaluated the prevalence of these illnesses in patients with severe asthma. METHODS We conducted a retrospective analysis of data obta...

BACKGROUND Portal hypertension in patients with liver cirrhosis causes manifestations such as esophageal varices, ascites and edema. Some studies have been conducted about the role of esophageal varices in the development of esophageal motor disorders and abnormal gastroesophageal reflux in these patients. Ascites could be a factor promoting gastroesophageal reflux and it has been questioned wh...

Gastroesophageal reflux disease is the most common esophageal disorder encountered in the United States. Gastroesophageal reflux disease symptoms are associated with a negative quality of life and increased healthcare costs and therefore require an effective management strategy. Although proton pump inhibitors remain the primary treatment of gastroesophageal reflux disease, they do not cure the...

Background: Prevalence of gastroesophageal reflux disease (GERD) has increased in the last decades, and it is now one of the most common chronic and recurrent diseases. The present study aimed at determining the frequency of gender (sex) and age in Iranian patients with GERD symptoms.    Methods: In this study, 803 patients aged 11 to 84 years, with erosive and nonerosive gastroesoph...

Laparoscopic fundoplication is a treatment option for gastroesophageal reflux disease refractory to medical treatment. When deciding whether or not to undergo surgery, patients with refractory gastroesophageal reflux disease and esophageal motility disorder need to fully understand the operative procedure, postoperative complications, and residual symptoms such as dysphagia, globus sensation, a...

background: gastroesophageal reflux disease (gerd) is a common disorder in the western population but detailed population-based data in iran is limited. the aim of this study was to investigate the prevalence of gerd in esfahan. materials and methods: a population-based study was conducted in 2004. major gerd symptoms (heartburn and acid regurgitation) were assessed through an interview by six ...

introduction and aims: gastroesophageal reflux disease (gerd) is very common in western countries. gerd is increasing, has profound effects on health economics, disturbs the patient's health-related quality of life, and increases the risk for development of esophageal adenocarcinoma. gerd is considered to be infrequent in developing countries. this study was performed to determine the prevalenc...

background: gastroesophageal reflux disease (gerd) is one of the most prevalent disorders affecting gastrointestinal tract with a wide range of frequency around the world. in this study, we aimed to review all of the published studies about gerd’s prevalence in iran systematically. methods: we searched bibliographic databases including pubmed and google scholar and local databases (scientific i...

Gastroesophageal reflux is the involuntary movement of gastric contents to the esophagus. It is a common disease, occurring in one third of the population in the United States. However, reflux is only considered a disease when it causes frequent or severe symptoms or when it produces injury. About 3–7% of the U.S. population suffers from frank esophageal reflux disease. Most reflux disease is n...

Gastroesophageal reflux disease often presents as heartburn and acid reflux, the so-called "typical" symptoms. However, a subgroup of patients presents a collection of signs and symptoms that are not directly related to esophageal damage. These are known collectively as the extraesophageal manifestations of gastroesophageal reflux disease. Principal among such manifestations are bronchospasm, c...