نتایج جستجو برای: gastroesophageal junction adenocarcinoma

تعداد نتایج: 122888  

2011
Jong Jin Hyun Young-Tae Bak

The relationship between hiatal hernias and gastroesophageal reflux disease (GERD) has been greatly debated over the past decades, with the importance of hiatal hernias first being overemphasized and then later being nearly neglected. It is now understood that both the anatomical (hiatal hernia) and the physiological (lower esophageal sphincter) features of the gastroesophageal junction play im...

Journal: :Archives of surgery 1999
S Oberg J H Peters J J Nigro J Theisen J A Hagen S R DeMeester C G Bremner T R DeMeester

HYPOTHESIS Helicobacter pylori is not associated with gastroesophageal reflux disease and its complications, including adenocarcinoma of the esophagus and the gastroesophageal junction (GEJ). DESIGN Retrospective analysis. SETTING University tertiary referral center. PATIENTS Two hundred twenty-nine patients with symptoms suggestive of foregut disease underwent esophageal manometry, 24-ho...

Journal: :International journal of cancer 2016
Jennifer Drahos Qian Xiao Harvey A Risch Neal D Freedman Christian C Abnet Lesley A Anderson Leslie Bernstein Linda Brown Wong-Ho Chow Marilie D Gammon Farin Kamangar Linda M Liao Liam J Murray Mary H Ward Weimin Ye Anna H Wu Thomas L Vaughan David C Whiteman Michael B Cook

Esophageal (EA) and esophagogastric junction (EGJA) adenocarcinoma have been steadily increasing in frequency in younger people; however, the etiology of these cancers is poorly understood. We therefore investigated associations of body mass index (BMI), cigarette smoking, alcohol consumption, gastroesophageal reflux and use of nonsteroidal anti-inflammatory drugs (NSAIDs) in relation to age-sp...

Journal: :Oncology 2002
Jaffer A Ajani Jackie Baker Peter W Pisters Linus Ho Paul F Mansfield Barry W Feig Chusilp Charnsangavej

We conducted a phase II study to assess the response rate and toxicity profile of the irinotecan (CPT-11, Camptosar) plus cisplatin combination administered weekly to patients with at least one previous chemotherapy for advanced adenocarcinoma of the stomach or gastroesophageal junction. Patients with histologic proof of adenocarcinoma of the stomach orgastroesophageal junction with adequate li...

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