Objective: To study the gastric anti-secretory and cytoprotective action of ethanolic extract of leaves of Andrographys paniculata. Methods: Effect of ethanolic extract of leaves of A. paniculata gastro-antisecretory and cytoprotective activity was studied in vivo by using gastric wall mucus determination, hypothermic restraint stress-induced ulcers, idomethacin-induced gastric ulcers, reserpin...

Study was made of the developmental mechanism of histamine induced ulcers and inhibitory effects of receptor antagonists from the view point of gastric acidity and microvasculature of the gastric mucosa, and the following results were obtained. 1. In histamine induced ulcers, hypersecretion of gastric acid caused by histamine is not the primary developmental mechanism of the lesion. The main ca...

Persian oak (Quercus brantii Lindl., the Fagaceae family) is a medicinal plant which seed flour is used to treat inflammatory and gastric ulcers by the tribes in southwestern Iran. The current study was done to evaluate the effect of hydro-alcoholic extract of Q. brantii seed flour for treatment of gastric ulcers induced by ethanol in Wistar rats. The hydro-alcoholic extract of Q. brantii was t...

Persian oak (Quercus brantii Lindl., the Fagaceae family) is a medicinal plant which seed flour is used to treat inflammatory and gastric ulcers by the tribes in southwestern Iran. The current study was done to evaluate the effect of hydro-alcoholic extract of Q. brantii seed flour for treatment of gastric ulcers induced by ethanol in Wistar rats. The hydro-alcoholic extract of Q. brantii was t...

Background: Data suggest that V. arctostaphylos, B. thunbergii var. atropurpurea, E. angustifolia and L. acanthodes may prevent gastric ulcers induced by Non-steroidal anti-inflammatory drugs (NSAIDs). Objective: To explore the ulcer-protective potential of these plants in indomethacin-induced gastric ulcers in rats. Methods: Saline, hydro-alcoholic extract of each plant (100, 400, 800 mg/...

Gastric ulcers are common in horses, with a prevalence estimated from 53 to 93%.1-3 Gastric ulcers can lead to decreased performance, vague clinical signs and may go undiagnosed for months. Gastric ulcers are primarily caused by stomach acids. However, the anatomy of the stomach, diet, restricted feed intake, exercise, stress (stall or transport), and the use of non-steroidal anti-inflammatory ...

1. Maximal acid output after pentagastrin stimulation, and fasting and postprandial serum gastrin concentrations were determined in 25 normal subjects, 30 patients with corpus gastric ulcers, 10 patients with prepyloric ulcers and 30 patients with both duodenal and gastric ulcers. 2. Corpus ulcers and prepyloric ulcers formed one distinct group. Maximal acid output was abnormally low in the cor...

Background This study aimed to evaluate the effects of the position of an acetic acid-induced gastric ulcer and the effects of prokinetic drugs on gastric emptying. Materials and Methods Male Sprague-Dawley rats were used in this study. Acetic acid ulcers were induced either in the region between the fundus and pylorus on the anterior wall of the stomach or in the glandular region on the greate...

Helicobacter pylori is a risk factor for gastric and duodenal ulcers, but gastric ulcers generally occur in individuals who have low acid production and diffuse gastritis, whereas duodenal ulcers are more likely to occur with high acid output and antrum-predominant gastritis. Low acid production, gastritis, and ulcer healing each contribute to poor antioxidant absorption, oxidative stress, and ...