BACKGROUND Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with Helicobacter pylori infection and H. pylori eradication is used as its first-line therapy. However, controversies exist about the prognostic value of H. pylori infection in these patients. We evaluated the prognostic impact of H. pylori infection and eradication therapy in gastric MALT lymphoma. METHODS A ...

BACKGROUND Treatment of primary gastric diffuse large B-cell lymphoma is still controversial. The treatment of localized disease was based on surgery alone, or followed by chemotherapy and/or radiotherapy. High-grade gastric lymphomas are generally believed to be Helicobacter pylori (HP)-independent growing tumors. However a few cases of regression of high-grade gastric lymphomas after the cure...

Gastric tumors share many characteristics, making a definitive diagnosis challenging. Gastric adenocarcinomas represent 90% of malignant stomach tumors, meanwhile the frequency of gastric lymphoma range between 1-5% of all gastric cancers. Gastric carcinoma bears resemblance with particular forms of non-Hodgkin's lymphoma of the stomach, not only in morphological presentation, but also in clini...

Primary gastric T cell lymphoma is rare and mostly of large cell type. In this paper, we present a case of gastric T cell lymphoma morphologically similar to the gastric marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (MALT). Morphologically, the cells are small with abundant clear cytoplasm. Lymphoepithelial lesions are readily identified with diffuse destruction of gastric ...

Among 121 cases of primary gastric malignant lymphoma from 1962 to 1994 at the National Cancer Center Hospital, Tokyo, we found four cases (three males and one female) of adenocarcinoma coexisting in the stomach. The incidence of gastric malignant lymphoma together with gastric adenocarcinoma was 3.3%, suggesting that patients with lymphoma may have an increased incidence of gastric adenocarcin...

Despite the decreasing incidence and mortality from gastric cancer, it remains a major health problem worldwide. Ninety percent of cases are adenocarcinomas. Here, we report a case of gastric adenocarcinoma developed after successful treatment of prior primary gastric diffuse large B-cell lymphoma (DLBCL). Our patient was an elderly man with primary gastric DLBCL in whom complete remission was ...

Gastric adenocarcinoma developing concomitantly with a gastric lymphoma of the mucosa-associated lymphoid tissue (MALT) type is rare. Herein, we report a case with a synchronous primary gastric MALT lymphoma and an early adenocarcinoma of the stomach. A 72-year-old patient with initial presentation of weight loss was found with endoscopy to have a large tumor mass in the gastric body. Pathologi...

We explored two cases of CD20-positive cytotoxic T cell lymphoma, a gastric lymphoma and an intestinal lymphoma. Neoplastic cells of the gastric lesion, possessing small cleaved-like nuclei with dense nuclear chromatin, infiltrated the mucosa in association with disappearance of the gastric glands. Neoplastic cells of the intestinal case had large, round nuclei with conspicuous nucleoli, with u...

The majority of malignant tumors of the stomach are carcinomas. It has been reported in the literature that lymphomas consist of 1%-5% of all malignant tumors of the stomach (1). The simultaneous coexistence of adenocarcinoma and malignant lymphoma of the stomach is extremely rare (1-5). Gastric carcinoma and primary gastric lymphoma have shown to be related to Helicobacter pylori infection (3)...

We herein report a patient who presented with follicular lymphoma. Although the stomach was initially intact, mucosal redness and multiple erosions appeared in gastric body owing to infiltration of lymphoma cells. Subsequently, slightly depressed, white area lacking structure detected lesser curvature cardia body, where cell also pathologically observed beneath stratified squamous epithelium. T...