The stomach is a sensitive digestive organ that is susceptible and exposed to exogenous pathogens from the diet. In response to such pathogens, the stomach induces oxidative stress, which might be related to the development of gastric organic disorders such as gastritis, gastric ulcers, and gastric cancer, as well as functional disorders such as functional dyspepsia. In particular, the bacteriu...

  Background: Saffron is the dried stigmata of the flowers of saffron (Crocus sativus L., Iridaceae). Saffron is well known for the treatment of gastric disorders in traditional medicine.   Objectives: In the search for new potential antiulcer agents, the effects of the ethanol extract of saffron and its active constituents crocin and safranal as compared with omeprazole against gastric ulcer i...

BACKGROUND AND AIMS Disorders of gastrointestinal transit and motility are frequently found in the general population, impacting the quality of life and increasing the costs of health care services. Ultrasonographic assessment of gastric emptying is a method introduced in the early 1980s for the evaluation of dyspepsia. The aim of this paper was to assess the current role of abdominal ultrasoun...

Background: Chronic inflammation and dys-regulation of the immune system mechanisms are now well established as primary triggers of gastric cancer and peptic ulcer disease. Galectin-9 (Gal-9) is a member of the galectin family and known as an inducer of cell aggregation, adhesion and apoptosis. Gal-9 interaction with its main ligand T-cell immunoglobulin and mucin domain protein-3 (Tim-3) leads...

background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron is well known for the treatment of gastric disorders in traditional medicine.   objectives: in the search for new potential antiulcer agents, the effects of the ethanol extract of saffron and its active constituents crocin and safranal as compared with omeprazole against gastric ulcer ind...

Background: Cytotoxin-associated gene A (CagA)-positive strains of Helicobacter pylori are associated with gastroduodenal diseases. Evidences have suggested that the type of H pylori CagA EPIYA motifs may be associated with specific disorders (i.e., gastritis, peptic ulcer, or gastric cancer).  We investigated the prevalence of different EPIYA motifs (A, B, C, or D) in H. pylori strains is...

Details about gastric physiology and pathophysiology are described. Other methods, some of them not used today, are also mentioned. Gastric emptying by radionuclides is important for checking normal function of the upper digestive system. The fried eggs etc. technique and not the liquid meal technique is preferred. In conclusion, gastric emptying by radionuclides, although other techniques have...

BACKGROUND Pharmacological approaches to alter satiation may have an impact on functional upper gastrointestinal disorders and potentially change food intake in obesity. AIM Our aim was to compare the effects of two doses of octreotide and placebo on postprandial symptoms, gastric accommodation, and gastric emptying using validated non-invasive techniques. METHODS In a randomised, parallel ...