A new paradigm for an effective delivery of therapeutics into cancer cells is presented. Degradable porous silicon carriers, which are tailored to carry and release a model anti-cancer drug, are biolistically bombarded into in-vitro cancerous targets. We demonstrate the ability to launch these highly porous microparticles by a pneumatic capillary gene gun, which is conventionally used to delive...

Impressive gains have been made in thermal spray coatings through material development and coating parameter selection. Nevertheless, it is usually up to shop personnel to develop a robot program to achieve the final coating. Coating programs are often developed using trial and error. Some motion and deposit analysis programs are available [1], [2]. However, they can be costly and require a lev...

A 60 kV neutral lithium diagnostic beam probes the edge plasma of JET for the measurement of electron density profiles. This paper describes recent enhancements of the diagnostic setup, new procedures for calibration and protection measures for the lithium ion gun during massive gas puffs for disruption mitigation. New light splitting optics allow...

Abstract The interior ballistic potential equilibrium theory is used to analyse the parameters at points of pressure curves 30mm conventional launching experiment and electrothermal-chemical (ETC) experiments. Analysis shows that: compared experiment, (1) time for ETC arrive point apparently shortened; (2) relative burnt percentages propellants are smaller in tests. And gas generation brisance ...

The study of target injection, detection, measurement of laser focal point, and laser beam steering have started under co-research in Japan. The smooth-bore gas gun is developed for accurate injection. The applications of divergent laser beam and Arago spot are described for accurate measurement of target position and laser focal point. Magnetic lens for target trajectory adjustment by centerin...

IMPORTANCE Gun violence and injuries pose a substantial threat to children and youth in the United States. Existing evidence points to the need for interventions and policies for keeping guns out of the hands of children and youth. OBJECTIVES (1) To examine the association between state gun law environment and youth gun carrying in the United States, and (2) to determine whether adult gun own...

Twenty rounds vere fired with the 15 gr. Modified M22 primers. A mean deviation of 2 f/s or an estimated probable error in velocity of 1.5 f/s was obtained. An explanation of this low dispersion in velocity is tentatively offered. Authority was ohtnin^d to fire a 20 round uniformity series in a 75 mm Gun Mod. 1G97 using charges of S.P. FNH, powder lot 5530, ignited with a 15 gr. Modified M22 pr...

A widely publicized but unpublished study of the relationship between gun shows and gun violence is being cited in debates about the regulation of gun shows and gun commerce. We believe the study is fatally flawed. A working paper entitled "The Effect of Gun Shows on Gun-Related Deaths: Evidence from California and Texas" outlined this study, which found no association between gun shows and gun...