In this work, ZnCaO2 (zinc oxide-calcium oxide) nanocomposite were synthesized at different temperatures (500-700°C) by sol-gel method based on polymeric network of polyvinyl alcohol (PVA). The synthesized samples were characterized by SEM/EDAX, FT-IR and XRD techniques. It was found that synthesized nanocomposites have 1.62, 2.05 and 13.91%wt of CaO, respectively. The obtained results show tha...

Dracocephalum kotschyi (Lamiaceae), as one of the remarkable aromatic plants, widely grows and also is cultivated in various temperate regions of Iran. There are diverse reports about the composition of the oil of this plant representing limonene derivatives as its major compounds. There is no report on cloning of monoor sesquiterpene synthases from this plant. In the present study, the aroma p...

OBJECTIVE The alteration of steroid hormonal status in premenopausal breast disease (benign and malignant) were investigated by comparing the urinary profile of androgens and corticoids. METHODS The urinary concentrations of 25 androgens and corticoids were quantitatively determined by a gas chromatographymass spectrometry system in patients with benign breast disease (35 cases, 20-54 years),...

In the present study, the safety and toxicity of Dendrophthoe pentandra (DP) extracted using ethyl acetate were investigated. DP ethyl acetate (DPEA) extract was screened for its phytochemical constituents using standard procedure and active compounds present in DPEA extract were determined using gas chromatographymass spectrometry (GC-MS), the toxicity of DPEA extract was investigated using br...

Background: The present study examines the various complications and impurities of alcoholbased hand sanitizers during COVID-19 among health workers in Hamadan City, Iran. Methods: This cross-sectional was conducted on 178 healthcare different hospitals affiliated with University Medical Sciences. inclusion criteria included personnel working dedicated to care treatment patients City. A researc...

In this study, encapsulation of agarwood oil with non-ionic surfactant, Tween 80 was prepared at critical micelle concentration of 0.0167 % v/v to produce the most stable nano-emulsion in aqueous. The encapsulation has minimized the bioactive compounds degradation in various pH conditions thus prolong their shelf life and maintained its initial oil grade. The oil grading of the prepared samples...

Primary carnitine deficiency (PCD) is a rare autosomal recessive disorder, caused by deficiency in the plasma membrane carnitine transporter. In this report, we aimed to describe the diagnosis and treatment of 12 PCD patients. Blood spots were collected from the children, and analysed using liquid chromatography-mass spectrometry (LC-MS). Newborns and children who had repeated lower dried blood...

We examined the possibility that renal glomerular and cortical tubular tissue has lipoxygenase activity in addition to the well established cyclo-oxygenase pathway of arachidonic acid metabolism. Homogenized rat kidney glomeruli, in the presence of meclofenamate (33 PM) and divalent cation ionophore A23187 (3 PM), metabolized octatritiated arachidonic acid to 12-hydroxyeicosatetraenoic acid and...

Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is an integral membrane protein of the smooth endoplasmic reticulum. However, we detected an HO-1 immunoreactive signal in the nucleus of cultured cells after exposure to hypoxia and heme or heme/hemopexin. Under these conditions, a faster migrating HO-1 immunoreactive band was enriched in nuclear extracts, suggesting that H...