1. Experimental results Figure S1: (a) Representative SEC chromatogram, obtained for a sample incubated 35 min at the protein concentration of 40 g/L. The portion of the chromatogram used for aggregate characterization by inline light scattering is comprised between the two dotted lines, i.e. between 15.1 and 17.7 min. (b) Correlation function measured by inline dynamic light scattering at the ...

Increasing importance of pharmaceutical plants in the world and the presence of many of these plants in our country, which has one of the richest Flora of the world, suggest the need for comprehensive studies. Research of secondary metabolites of medicinal and essential oily plants from Iran’s dry to super dry deserts is very important. One of the most famous species from “Labiatae” family is D...

The potential for the utilization of GC x GC-time-of-flight (TOF) MS for high-resolution metabolomics studies is discussed, with the implementation of some statistical comparisons for biomarker detection. Metabolite profiles from NZO obese mice versus BL/6 control mice are compared and contrasted using a number of chromatogram comparison routines, including direct chromatogram comparisons, chro...

UNLABELLED Chromaligner is a tool for chromatogram alignment to align retention time for chromatographic methods coupled to spectrophotometers such as high performance liquid chromatography and capillary electrophoresis for metabolomics works. Chromaligner resolves peak shifts by a constrained chromatogram alignment. For a collection of chromatograms and a set of defined peaks, Chromaligner ali...

Summary: Chromaligner is a tool for chromatogram alignment to align retention time for chromatographic methods coupled to spectrophotometers such as high performance liquid chromatography and capillary electrophoresis for metabolomics works. Chromaligner resolves peak shifts by a constrained chromatogram alignment. For a collection of chromatograms and a set of defined peaks, Chromaligner align...

To understand the ultimately lowest detection range of volatile organic compounds (VOCs) in air, application of a high sensitivity analytical system was investigated by coupling thermal desorption (TD) technique with gas chromatography (GC) and time-of-flight (TOF) mass spectrometry (MS). The performance of the TD-GC/TOF MS system was evaluated using liquid standards of 19 target VOCs prepared ...

As columns age and differ between systems, retention times for comprehensive two-dimensional gas chromatography (GCxGC) may vary between runs. To properly analyze GCxGC chromatograms, it often is desirable to align the retention times of chromatographic features, such as analyte peaks, between chromatograms. Previous work by the authors has shown that global, low-degree polynomial transformatio...