Radionuclide therapy extends the usefulness of radiation from localized disease of multifocal disease by combining radionuclides with disease-seeking drugs, such as antibodies or custom-designed synthetic agents. Like conventional radiotherapy, the effectiveness of targeted radionuclides is ultimately limited by the amount of undesired radiation given to a critical, dose-limiting normal tissue,...

Radiation dosimetry in protection against ionising radiation involves research of all possible pathways through which natural or man-made radioactive materials can contaminate a habitat and actually harm its biota. It also takes into account natural and artificial (man-made) electromagnetic ionizing radiation (gamma and x radiation). This article presents a dosimetric study assessing exposure t...

Background: Absolute dosimetry of external beam radiotherapy is carried out by the use of ionization chambers. These chambers must be calibrated at a standard dosimetry laboratory before any use in clinical dosimetry. The secondary standard dosimetry laboratory of Iran (SSDL) has the duty of calibrating the ionization chambers used in radiotherapy centers in Iran. Materials and Methods...

background: hydrogen peroxide (h2o2), produced by gamma ray irradiation to watery solution, was used as an analytical parameter for dosimetry of cobalt-60 (60co) radiation. materials and methods: detection of the produced h2o2 was carried out using two methods: an amperometric biosensor fabricated by immobilization of anthraquinone 2-carboxylic acid modified horseradish peroxidase on glassy car...

We investigated post-irradiation variations of the radiation induced attenuation (RIA) polymer perfluorinated (CYTOP) optical fiber exposed to gamma radiation. The RIA measured five months after irradiation was qualitatively similar that several hours irradiation. However, quantitatively evolution significantly depends on spectral range: in visible range, transmission partly recovers, while inf...

We present commissioning and comprehensive evaluation for ArcCHECK as a QA equipment for volumetric-modulated arc therapy (VMAT), using the 6 MV photon beam with and without the flattening filter, and the SNC patient software (version 6.2). In addition to commissioning involving absolute dose calibration, array calibration, and PMMA density verification, ArcCHECK was evaluated for its response ...

A commercial optically stimulated luminescence (OSL) system developed for radiation protection dosimetry by Landauer, Inc., the InLight microStar reader, was tested for dosimetry procedures in radiotherapy. The system uses carbon-doped aluminum oxide, Al2O3:C, as a radiation detector material. Using this OSL system, a percent depth dose curve for 60Co gamma radiation was measured in solid water...

OBJECTIVE In radiation treatment, the irradiation which is effective enough to control the tumors far exceeds normal-tissues tolerance. Thus to avoid such unfavourable outcomes, some methods sensitizing the tumor cells to radiation are used. Iododeoxyuridine (IUdR) is a halogenated thymidine analogue that known to be effective as a radiosensitizer in human cancer therapy. Improving the potentia...