The correlation between tubocurarine requirements and the electrophoretic serum protein pattern was investigated in 52 adult patients undergoing upper abdominal surgery under nitrous oxide and oxygen anaesthesia. There was a positive correlation between the tubocurarine requirements (mg/kg) and the serum level of gamma globulin; r = +0.604, which is highly significant (P<0.001). This correlatio...

1. Antibody produced in the horse migrates as a new serum component between the beta and gamma components, whereas rabbit antibody is electrophoretically identical with the gamma globulin component of the serum. 2. In rabbit and monkey antisera the percentage of antibody in the serum and in the gamma globulin fraction can be determined by integration of the electrophoresis diagrams of unabsorbe...

In the chicken, serum gamma globulin (CGG) is preferentially transferred by the follicular epithelium of the ovary to the developing ova. The concentration of gamma globulin in the yolk of the unfertilized egg is many times the concentration of chicken serum albumin (CSA). This transfer occurs largely during the 4 to 5 days preceding ovulation when the growth of the ovum is most rapid. Thus, in...

The earlier observed pronounced hypogammaglobulinemia in germfree rats of different ages has been confirmed. Using an immunologic technique the concentration of immunologic gamma globulins were found to vary between 10 and 15 per cent of the values observed in ordinary rats. Upon contamination of germfree rats with the normal microbial flora a pronounced lag phase was noted before the gamma glo...

Fluorescein-labelled aggregated human gamma-globulin was found to react in precipitin-type tests with serums of individuals with rheumatoid arthritis. This reagent was also highly reactive and specific for the localization of rheumatoid factor in frozen sections of synovial membranes, lymph nodes, and subcutaneous nodules. In synovial membranes from patients with active rheumatoid arthritis, rh...

Rheumatoid factors in the sera of patients with rheumatoid arthritis appear to be specifically directed against genetically determined "antigens" in human gamma-globulin. At least eight rheumatoid factors of differing specificity exist; usually several are present in combination in the same serum. The different rheumatoid factors can be readily detected through their pattern of reactivity with ...

Myeloma gamma globulins have been reported to interfere with fibrinogen-fibrin conversion. A patient with multiple myeloma is described with a gamma globulin IgG1lambda concentration of 11 g per dl, prolonged thrombin time and poor clot retraction. Purified gamma globulin from the patient's serum and from normal serum caused prolongation of the thrombin time and reptilase clotting time assays i...

This review informs about the chemical composition of plasma proteins majorly albumin and globulin. Blood proteins, also called are found in blood plasma. While, serum present human body very high quantities for other proteins. Hundreds dissolved but only two major protein groups i.e. Albumin Globulin. is a important component (55% proteins) it made by liver. There an immediate correlation betw...

the study on the serum protein electrophoresis following thyroidectomy in a puppies showed a significant decrease in the albumin and -a-ratio associated with a relative increase in gamma and total globulin, but alterations of alpha i and beta globulin were not statistically charcteristic in our thyroidectomized dogs.