The GAGE family of tumor-associated antigens is present in a wide spectrum of human tumors but is highly restricted among normal tissues except to the testis. By reverse transcription-PCR, GAGE expression was detected in 55 of 67 neuroblastomas (NBs; 8 of 12 stage 1, 13 of 13 stage 2, 9 of 12 stage 3, 7 of 12 stage 4S, and 18 of 18 stage 4), 5 of 5 Ewing's and peripheral neuroectodermal tumors,...

The need for calibration arises frequently in the use of strain gage instrumentation. Periodic calibration is required, of course, to assure the accuracy and/or linearity of the instrument itself. More often, calibration is necessary to scale the instrument sensitivity (by adjusting gage factor or gain) in order that the registered output correspond conveniently and accurately to some predeterm...

With the advent of rapid genome sequencing, the view of the human genome as a vast desert dotted with far-flung oases of functional genes has contended with a growing appreciation of the role of regulatory sequences in shaping gene expression. The fraction of the human genome’s noncoding component that can be considered functional remains to be established, but strewn across the seeming wastela...

The calculation of uncertainty for a measurement is an effort to set reasonable bounds for the measurement result according to standardized rules. Since every measurement produces only an estimate of the answer, the primary requisite of an uncertainty statement is to inform the reader of how sure the writer is that the answer is in a certain range. This report explains how we have implemented t...

Perhaps the most famous brain injury in history was a penetrating wound suffered by a rail road worker named Phineas Gage on September 13, 1848. Twelve years after his injury, on the 21st of May, 1860 Phineas Gage died of an epileptic seizure. In 1868 Dr. Harlow gave an outline of Gage's case history and first disclosed his remarkable personality change. One might think this report would assure...

BACKGROUND Cancer/testis antigens (CTAs) are expressed in several cancers and during normal adult male germ cell differentiation. Little is known about their role in fetal development of human germ cells. METHODS We examined expression of the CTAs MAGE-A1, GAGE and NY-ESO-1 in fetal gonads by single and double immunohistochemical staining. RESULTS We found that GAGE was expressed in the pri...

Strain gage rosettes are used often in engineering practice to determine strain states at specific points on a structure. Figure 1 illustrates three commonly used strain gage rosette configurations. Each of these configurations is designed with a specific task in mind. The far right rosette in Figure 1 is referred to as a tee rosette. Tee rosettes are two element rosettes and should only be use...

In Brazil, the correct measurement of individual firm energy a plant is important, since it influences directly determination its assured which used to establish contracts between power plants and distribution companies, free consumers, traders. With increasing technological development greater reliability in use automated techniques for monitoring, Acoustic Doppler Current Profiler (ADCP), has...

The purpose of this project is to set up a statistical process control (SPC) system in a high volume machining center to reduce the scrap rate and improve the manufacturing quality. The system is demonstrated on a machining center at Waters Corporation as part of a team internship project. This thesis focuses on the gage repeatability and reproducibility study (Gage R&R study) for the implement...