Basidiocarps of species of Armillaria, Russula, Lactarius and  Agaricus with fungal infection were collected from different regions of Iran. Portions of infected carpophores, were taken and cultured on PDA, PCA and MEA. Fungicolous isolates were identified on the basis of morphological characters such as: color and shape of colony, morphology and branching of conidiophores, manner of proliferat...

BACKGROUND Fungal morphology and aeration play a significant role in the growth process of Mortierella alpina. The production of microbial oil rich in arachidonic acid (ARA) in M. alpina was enhanced by using a multi-stage fermentation strategy which combined fed-batch culture with precise control of aeration and agitation rates at proper times. RESULTS The fermentation period was divided int...

Head blight, which is caused by mycotoxin-producing fungi of the genus Fusarium, is an economically important crop disease. We assessed the potential of host-induced gene silencing targeting the fungal cytochrome P450 lanosterol C-14α-demethylase (CYP51) genes, which are essential for ergosterol biosynthesis, to restrict fungal infection. In axenic cultures of Fusarium graminearum, in vitro fee...

BACKGROUND In order to better understand the possible role of fungi in giant panda reproduction and overall health, it is important to provide a baseline for the normal fungal composition in the reproductive system. Using morphology and internal transcribed spacer (ITS) sequence analysis, we systematically isolated and identified fungal species from the vagina, foreskin, and semen of 21 (11 mal...

Morphological changes are a very common and effective strategy for pathogens to survive in the mammalian host. During interactions with their host, human pathogenic fungi undergo an array of morphological changes that are tightly associated with virulence. Candida albicans switches between yeast cells and hyphae during infection. Thermally dimorphic pathogens, such as Histoplasma capsulatum and...

microbial corneal diseases are a serious ocular infection and the major cause of ocular morbidity and blindness in the world. the outcomes of fungal keratitis are unfavorable due to the protracted course of the condition and the diversity of respective clinical presentations. trauma, contact lens wear, foreign material, and prior corneal surgery, may make the most background for permitting inva...

Discriminating between commensal and pathogenic states of opportunistic pathogens is critical for host mucosal defense and homeostasis. The opportunistic human fungal pathogen Candida albicans is also a constituent of the normal oral flora and grows either as yeasts or hyphae. We demonstrate that oral epithelial cells orchestrate an innate response to C. albicans via NF-κB and a biphasic MAPK r...

During 2002-03 forty-four different barley growing regions in East Azarbaijanprovince of Iran were sampled for epiphytic fungi. Isolation of fungi was achieved using standard methods. As the result 374 hyphomycetous isolates were obtained that were placed in 22 genera and 49 species based on colony morphology and microscopic features (Table 1). Among these, Acremonium egyptiacum, A. sclerotigen...

The fungal kingdom potentially has the most complex chitin synthase (CHS) gene family, but evolution of the fungal CHS gene family and its diversification to fulfill multiple functions remain to be elucidated. Here, we identified the full complement of CHSs from 231 fungal species. Using the largest dataset to date, we characterized the evolution of the fungal CHS gene family using phylogenetic...

Cryptococcus neoformans is an encapsulated fungus that causes cryptococcosis. Central nervous system infection is the most common clinical presentation followed by pulmonary, skin and eye manifestations. Cryptococcosis is primarily treated with amphotericin B (AMB), fluconazole (FLC) and itraconazole (ITC). In the present work, we evaluated the in vitro effect of terbinafine (TRB), an antifunga...