In order to therapeutically destroy oncological neoplasms, chemotherapy or radiotherapy is usually applied, and in isotope medicine – short-lived radio nuclides are injected into the tumor ( 59 Fe, 90 Y, 95 Zr, 99m Tc, 106 Ru, 114* In, 147 Eu, 148 155 170 Tm, 188 Re, 210 Po, 222 Rn, 230 U, 237 Pu, 240 Cm, 241 253 Es). Binary (or neutron capture) therapy a technology developed for selective effe...

Fullerenols, water-soluble C60-fullerene derivatives, have been shown to exert neuroprotective effects in vitro and in vivo, most likely due to their capability to scavenge free radicals. However, little is known about the effects of fullerenols on the blood-brain barrier (BBB), especially on cerebral endothelial cells under inflammatory conditions. Here, we investigated whether the treatment o...

In order to therapeutically destroy neoplasms, chemotherapy or radiotherapy is usually applied, and in isotope medicine short-lived radionuclides are injected into the tumor ( 59 Fe, 90 Y, 95 Zr, 99 mTc, 106 Ru, 114* In, 147 Eu, 148 155 170 Tm, 177 mLu, 188 Re, 210 Po, 222 Rn, 230 U, 237 Pu, 240 Cm, 241 253 Es). Binary (or neutron capture) therapy a technology designed selectively treat maligna...

One of the methods for treating oncological diseases is application short-lived radionuclides. Existing risks intoxication and radioactive contamination can be eliminated by introduction a radon isotope into hard strong fullerene coat. To increase effectiveness these drugs it promising to introduce structural fragments amino acids, peptides, steroid hormones, nucleic bases or heterocyclic compo...