Background: Equine wounds, particularly those involving the distal portion of the limbs, often undergo prolonged complex healing and may enter a non-healing state with obvious financial and welfare implications. Poor blood supply and lower levels of oxygen to the lower limbs lead to imbalance of growth factors related to wound healing. Decellular amniotic membrane has been widely used in soft t...

BACKGROUND Conventional autologous skin grafts are associated with significant donor-site morbidity. This study was conducted to determine feasibility, safety, and efficacy of a new strategy for skin grafting based on harvesting small columns of full-thickness skin with minimal donor-site morbidity. METHODS The swine model was used for this study. Hundreds of full-thickness columns of skin ti...

BACKGROUND Full-thickness skin graft (FTSG) is a very versatile tool regularly used in small sizes. With the established knowledge of the graft take through the margins as well as wound bed, we extended the use of the FTSG for reconstruction of large-sized defects with satisfactory results.  METHODS We presented our experience in wound reconstruction using FTSG in 28 patients. We select...

INTRODUCTION Xenograft transplantation, first performed in the early 20th century, has been used successfully in traumatic wounds, burns, chronic ulcers, and surgical defects. Xenografts should be considered when facing not only limited donor skin or multiple patient comorbidities that may preclude successful full thickness skin grafting, but also unusually large surgical defects. Xenografts ar...

objective(s) wound licking has been shown to advance wound healing among humans and many other animals. the present study evaluates the licking effects on healing of skin wound in rats. materials and methods twenty four rats were assigned to 4 different groups randomly and two 3 cm longitudinal full thickness incisions were made on each dorsal and ventral side of rats. the ventral incisions wer...

Full-thickness burns destroy both the epidermal and dermal tissues of the skin. This study evaluates a collagen and chondroitin-6-sulfate dermal skin substitute (graft) that was applied to excised full-thickness burns and covered with Biobrane. Experimental conditions included: (a) no burn, subcutaneous implantation of the graft; (b) burn, excision, graft, coverage with Biobrane and bandages; (...

OBJECTIVE To examine the effectiveness of topical phenytoin in preserving the skin viability and increasing acceptance rate of autograft. METHODS We conducted this study in the Central Laboratory Animal House of Jordan University of Science and Technology, Irbid, Jordan during the period from September 2004 to June 2005. Forty-two rats were divided into 2 equal groups; full thickness dorsal s...

Background: Honey has been shown to accelerate wound healing, which is especially important in the management of patients with full-thickness wounds of skin in dermatologic