radiation-related wounds challenge surgeons in all disciplines of surgery. wound-healing complications are commonplace, and solutions for reconstruction are limited. muscle and musculocutaneous flaps have improved this situation. but the question is, does previous radiation of the muscle to be transposed affect the outcome? 143 consecutive previously irradiated patients treated with muscle or m...

The first suggestion that physical exercise results in free radical-mediated damage appeared in 1978, and since that time the sources of oxidant production during exercise continue to be debated. Many researchers focused on the damaging effects of oxidants in muscle (oxidative damage of proteins and lipids), but the examination of cell-signaling effects of free radicals on muscle activity becam...

  Leiomyosarcoma in birds is relatively rare. This tumor as a muscle neoplasm was reported in captive and free ranging birds. Smooth muscle cells may develop to the leiomyosracoma, but splenic smooth muscle trabeculae is most common site of the tumor growth. Although budgerigars have an incidence of neoplastic diseases but smooth muscle tumors were rarely reported in this species. To the best o...

objective(s): pregabalin (pgb) is a new antiepileptic drug that has received fda approval for patient who suffers from central neuropathic pain, partial seizures, generalized anxiety disorder, fibromyalgia and sleep disorders. this study was undertaken to evaluate the possible adverse effects of pgb on the muscular system of mice. materials and methods: to evaluate the effect of pgb on skeletal...

neglected, untreated and delayed femur neck fractures are commonly encountered and the treatment dilemma arises especially when the patient is physiologically young and osteosynthesis is the preferred option. controversy exists in the current literature as the various head salvage surgeries like valgus subtrochanteric osteotomy, non-vascularized fibular bone grafting, muscle pedicle bone grafti...

BACKGROUND The increase in cytosolic free Mg2+ occurring during exercise and initial recovery in human skeletal muscle is matched by a decrease in cytosolic pH as shown by in vivo phosphorus magnetic resonance spectroscopy (31P MRS). To investigate in vivo to what extent the homeostasis of intracellular free Mg2+ is linked to pH in human skeletal muscle, we studied patients with metabolic myopa...