Free radicals generated from alpha- and beta-ionyl bromides gave well resolved ESR spectra, but retinyl bromide and chloride gave only broad signals. Delocalised radicals were also spectroscopically observed on hydrogen abstraction from alpha-ionane, alpha-ionyltrimethylsilylether and buten-3-ynyl-2,6,6-trimethyl-2-cyclohexene. Retinyl and beta-ionyl radicals, derived from the corresponding xan...

A new split beta-lactamase assay promises experimental testing of the interplay of protein stability and function. Proteins are sufficiently stable to act effectively within cells. However, mutations generally destabilize structure, with effects on free energy that are comparable to the free energy of folding. Assays of protein functionality and stability in vivo enable a quick study of factors...

Recently a semiempirical method has been proposed by Aqvist et al. to calculate absolute and relative binding free energies. In this method, the absolute binding free energy of a ligand is estimated as deltaGbind = alpha + beta, where Vel(bound) and Vvdw(bound) are the electrostatic and van der Waals interaction energies between the ligand and t...

1. Structure-linked latency, a trait for most lysosome hydrolase activities, is customarily ascribed to the permeability-barrier function performed by the particle-limiting membrane, which shields enzyme sites from externally added substrates. 2. The influence of various substrate concentrations on the reaction rate has been measured for both free (non-latent) and total (completely unmasked by ...

We study the high temperature (or small inverse $\beta$) expansion of free energy double scaled SYK model. find that this is a convergent series with finite radius convergence. It turns out convergence determined by first zero partition function on imaginary $\beta$-axis. also show semi-classical obtained from saddle point approximation exact result consistent energy.

Understanding the phase transformation pathways (PTPs) and microstructural evolution in multi-phase HEAs will aid alloy process designs to tailor microstructures for specific engineering applications. In this work, we study two-phase where a disordered parent separates into mixture of two phases: an ordered ($\beta'$) + ($\beta$) upon cooling following different PTPs: (i) congruent ordering fol...

The beta-Amyloid peptide (A beta) is hypothesized to mediate the neurodegeneration seen in Alzheimer's disease. Recently, we proposed a new hypothesis to explain the toxicity of A beta based on the free-radical generating capacity of A beta. We have recently demonstrated using electron paramagnetic resonance (EPR) spectroscopy that A beta (1-40) generates free radicals in solution. It was there...

Let $R$ be a 2-torsion free ring and $U$ be a square closed Lie ideal of $R$. Suppose that $alpha, beta$ are automorphisms of $R$. An additive mapping $delta: R longrightarrow R$ is said to be a Jordan left $(alpha,beta)$-derivation of $R$ if $delta(x^2)=alpha(x)delta(x)+beta(x)delta(x)$ holds for all $xin R$. In this paper it is established that if $R$ admits an additive mapping $G : Rlongrigh...