BACKGROUND Overweight and obesity are positively correlated with increased risk of morbidity and mortality. AIM To evaluate whether obesity may be considered an independent cardiovascular risk factor in patients of ages from 35 to 74 years followed-up for 10 years. DESIGN OF STUDY Observational, longitudinal retrospective study. SETTING Primary care practices in Badajoz (Spain). METHOD ...

CONTEXT Data on cardiovascular risk (CVR) score among HIV-infected patients in sub-Saharan Africa are scarce. Our first objective was to compare the CVR score of Framingham utilizing BMI and lipids at baseline, and secondary to assess evolution of CVR score over time at Month 30 in the Temprano trial. METHODS HIV-infected adults with CD4 <800/mm3 without criteria for initiating ART were inclu...

INTRODUCTION This study aimed to determine the prevalence of metabolic syndrome and risk of coronary heart disease (CHD) in patients with schizophrenia receiving antipsychotics in Malaysia. METHODS This cross-sectional study, conducted at multiple centres, involved 270 patients who fulfilled the Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV-TR diagnostic criteria for schizoph...

OBJECTIVE To estimate stroke risk for diabetes, isolated or associated to metabolic syndrome (MS) according WHO and National Cholesterol Education Program (NCEP) criteria. DESIGN Multicentre and prospective cohort study. SETTING Primary health care. PARTICIPANTS Subjects between 55-85 years-old without any evidence of stroke, included from 1998 in a random population sample for MS follow-...

BACKGROUND AND PURPOSE Previous estimates of the prevalence of silent cerebral infarction (SCI) on MRI in community-based samples have varied between 5.8% and 17.7% depending on age, ethnicity, presence of comorbidities, and imaging techniques. We document the prevalence and risk factors associated with SCI at midlife in the community-based Framingham sample. METHODS Our study sample comprise...

Current methods of cardiovascular risk assessment are performed using health factors which are often based on the Framingham study. However, these methods have significant limitations due to their poor sensitivity and specificity. We have compared the parameters from the Framingham equation with linear regression analysis to establish the effect of training of the model for the local database. ...

Aim: The primary aim of this study is to investigate the effect presence Fibromyalgia(FM) on cardiovascular risk and cardiopulmonary capacity in diabetes mellitus (DM) patients. In addition, prevalence FM DM patients was investigated according American College Rheumatology (ACR) 2016 criteria.&#x0D; Material Methods: included 188 premenopausal female with Type 2 DM. physical activity level part...

BACKGROUND AND PURPOSE External validation of the Framingham stroke risk function has been rarely performed. We assessed its predictive ability in a population-based cohort of French elderly. METHODS The sample comprised 6913 subjects from the 3C Study, aged 65 to 84 at baseline, who were followed up to 6 years. Predictive accuracy of the original Framingham stroke risk function was assessed ...

BACKGROUND The utility of the Framingham risk score among individuals infected with HIV is poorly understood. We examined the association of Framingham risk scores with surrogate markers of atherosclerosis in a carefully characterized cohort of adults infected with HIV. METHODS We calculated Framingham risk scores and measured carotid intima-media thickness (c-IMT) and coronary artery calcium...

CONTEXT The Framingham Heart Study helped to establish tools to assess coronary heart disease (CHD) risk, but the homogeneous nature of the Framingham population prevents simple extrapolation to other populations. Recalibration of Framingham functions could permit various regions of the world to adapt Framingham tools to local populations. OBJECTIVE To evaluate the performance of the Framingh...