نتایج جستجو برای: fractional flow reserve

تعداد نتایج: 563105  

2014
Francesco Burzotta Antonio Maria Leone Giovanni Luigi De Maria Giampaolo Niccoli Valentina Coluccia Giancarlo Pirozzolo Silvia Saffioti Cristina Aurigemma Carlo Trani Filippo Crea

BACKGROUND The management of patients with angiographically intermediate coronary lesions is a major clinical issue. Fractional flow reserve provides validated functional insights while optical coherence tomography provides high resolution anatomic imaging. Both techniques may be applied to guide management in case of angiographically intermediate coronary lesions. Moreover, these techniques ma...

2016
Kranthi K. Kolli James K. Min Seongmin Ha Hilary Soohoo Guanglei Xiong

BACKGROUND The aim of this study was to investigate the impact of varying hemodynamic conditions on fractional flow reserve (ratio of pressure distal [Pd] and proximal [Pa] to stenosis under hyperemia) in an in vitro setting. Failure to achieve maximal hyperemia and the choice of hyperemic agents may have differential effects on coronary hemodynamics and, consequently, on the determination of f...

Journal: :Circulation 2016
Hyoung-Mo Yang Kiran Khush Helen Luikart Kozo Okada Hong-Seok Lim Yuhei Kobayashi Yasuhiro Honda Alan C Yeung Hannah Valantine William F Fearon

BACKGROUND The aim of this study is to determine the prognostic value of invasively assessing coronary physiology early after heart transplantation. METHODS AND RESULTS Seventy-four cardiac transplant recipients had fractional flow reserve, coronary flow reserve, index of microcirculatory resistance (IMR), and intravascular ultrasound performed down the left anterior descending coronary arter...

Journal: :Circulation. Cardiovascular interventions 2014
David A Chalyan Zhang Zhang Shigeho Takarada Sabee Molloi

BACKGROUND Diastolic fractional flow reserve (dFFR) has been shown to be highly sensitive for detection of inducible myocardial ischemia. However, its reliance on measurement of left-ventricular pressure for zero-flow pressure correction, as well as manual extraction of the diastolic interval, has been its major limitation. Given previous reports of minimal zero-flow pressure at end-diastole, w...

2015
Gilbert WM Wijntjens Martijn A van Lavieren Jan J Piek

2015 The complexity of ischemic heart disease (IHD) comprehends disease in the succeeding perfusion domains of the vascular tree. Fractional flow reserve and coronary flow reserve are validated diagnostic modalities to identify myocardial ischemia, but solitarily do not suffice to objectify the respective contribution of obstructive and nonobstructive disease to IHD. Combined pressure and flow ...

2017
Kara Shuttleworth Kristina Smith Jonathan Watt Jamie A. L. Smith Stephen J. Leslie

BACKGROUND The instantaneous wave-free ratio (iFR) is a novel method to assess the ischemic potential of coronary artery stenoses. Clinical trial data have shown that iFR has acceptable diagnostic agreement with fractional flow reserve (FFR), the reference standard for the functional assessment of coronary stenoses. This study compares iFR measurements with FFR measurements in a real world, sin...

2016
Harvey S. Hecht Jagat Narula William F. Fearon

Background: Invasive Fractional Flow Reserve Obstructive coronary artery disease (CAD) produces symptoms and increases the risk of adverse cardiac outcomes. However, determining whether a particular coronary stenosis is responsible for causing myocardial ischemia can be challenging, even with invasive coronary angiography (ICA). To help guide decisions in the cardiac catheterization laboratory,...

Journal: :Revista espanola de cardiologia 2003
Rafael J Ruiz-Salmerón Marcelo Sanmartín Ramón Mantilla Marisol Bravo Raúl Castellanos Javier Goicolea

Fractional flow reserve, as determined with a pressure-wire, was validated in the assessment of the functional severity of intermediate lesions in a population with stable ischemic cardiopathy. The value of pressure-wire analysis in acute coronary syndrome is unknown. We report two patients with acute coronary syndrome, in which the therapeutic approach was guided by the fractional flow reserve...

Journal: :Circulation. Cardiovascular interventions 2015
Sukhjinder S Nijjer Ricardo Petraco Tim P van de Hoef Sayan Sen Martijn A van Lavieren Rodney A Foale Martijn Meuwissen Christopher Broyd Mauro Echavarria-Pinto Rasha Al-Lamee Nicolas Foin Amarjit Sethi Iqbal S Malik Ghada W Mikhail Alun D Hughes Jamil Mayet Darrel P Francis Carlo Di Mario Javier Escaned Jan J Piek Justin E Davies

BACKGROUND Percutaneous coronary intervention (PCI) aims to increase coronary blood flow by relieving epicardial obstruction. However, no study has objectively confirmed this and assessed changes in flow over different phases of the cardiac cycle. We quantified the change in resting and hyperemic flow velocity after PCI in stenoses defined physiologically by fractional flow reserve and other pa...

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