نتایج جستجو برای: founder effect

تعداد نتایج: 1647862  

2018
Cecilie Heramb Teresia Wangensteen Eli Marie Grindedal Sarah Louise Ariansen Sheba Lothe Ketil Riddervold Heimdal Lovise Mæhle

Background Founder mutations in the two breast cancer genes, BRCA1 and BRCA2, have been described in many populations, among these are Ashkenazi-Jewish, Polish, Norwegian and Icelandic. Founder mutation testing in patients with relevant ancestry has been a cost-efficient approach in such populations. Four Norwegian BRCA1 founder mutations were defined by haplotyping in 2001, and accounted for 6...

2011
Dieter Anseeuw Joost A. M. Raeymaekers Paul Busselen Erik Verheyen Jos Snoeks

Peripheral isolated populations may undergo rapid divergence from the main population due to various factors such as a bottleneck or a founder effect followed by genetic drift or local selection pressures. Recent populations of two economically important Copadichromis species in Lake Malombe, a satellite lake of Lake Malawi, were neither genetically nor morphometrically distinct from their sour...

Journal: :Current Biology 1995
Brian Charlesworth

Experiments in which laboratory populations of fruitflies have been repeatedly passed through bottlenecks fail to support 'founder-effect' models of speciation.

2011
Alice Tagliani-Ribeiro Mariana Oliveira Adriana K. Sassi Maira R. Rodrigues Marcelo Zagonel-Oliveira Gary Steinman Ursula Matte Nelson J. R. Fagundes Lavinia Schuler-Faccini

Cândido Godói (CG) is a small municipality in South Brazil with approximately 6,000 inhabitants. It is known as the "Twins' Town" due to its high rate of twin births. Recently it was claimed that such high frequency of twinning would be connected to experiments performed by the German Nazi doctor Joseph Mengele. It is known, however, that this town was founded by a small number of families and ...

Journal: :Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2007

2011
N. Hofman R. Jongbloed P. G. Postema E. Nannenberg M. Alders A. A. M. Wilde

BACKGROUND AND OBJECTIVE: The long-QT syndrome (LQTS) is associated with premature sudden cardiac deaths affecting whole families and is caused by mutations in genes encoding for cardiac proteins. When the same mutation is found in different families (recurrent mutations), this may imply either a common ancestor (founder) or multiple de novo mutations. We aimed to review recurrent mutations in ...

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