Thyroid fine-needle aspiration (FNA) is a standard procedure for the clinical triage of thyroid nodules. The diagnosis of an adequately sampled thyroid FNA is generally grouped into three categories: benign, malignant, and indeterminate. The latter group usually includes follicular neoplasm, follicular lesion, and sometimes a more specific diagnosis such as Hurthle cell neoplasm or follicular l...

Thyroid cancer accounts for approximately 1% of all human cancers. Follicular carcinoma thyroid (FCT) is the second most common thyroid cancer after papillary carcinoma. Follicular carcinoma thyroid accounts for 10-15% of clinically evident thyroid malignancies. Follicular carcinoma thyroid commonly metastasize to lung and bone. Intracranial metastasis occurs in about only 1%. Follicular carcin...

HBME-l is an antimesothelial monoclonal antibody that recognizes an unknown antigen on microvilli of mesothelial cells. The antibody is only relatively specific for mesothelium and is used in the differential diagnosis of mesothelioma and adenocarcinoma within the context of an appropriate immuno-histochemical panel. HBME-l has also been reported to strongly and uniformly stain papillary and fo...

Follicular mucinosis is defined as the accumulation of mucin in the follicular epithelium and sebaceous glands.1 It can present in isolation with an unknown etiology2 or in association with several conditions, including various types of hematologic malignancy. We report the case of an 8-year-old girl with no medical history of interest who was referred for a lesion on the dorsum of the nose tha...

Background Follicular dendritic cell (FDC) sarcoma is an extremely rare neoplasm, which has only been reported once in the literature with an intracranial occurrence. Neither hemorrhagic presentation of an intracranial instance of FDC sarcoma nor its rapid recurrence has yet been published in the literature. Case Description We report the case of a 61-year-old female who presented with confus...

Tumor of follicular infundibulum (TFI) is a rare benign cutaneous appendage tumor that does not have characteristic clinical features. It mainly present in the head, neck, and trunk as solitary lesion. In particular, TFI typically manifests plate-like proliferation with multiple thin epidermal connections comprise monomorphic cells. do represent characteristics, but significance because associa...

with confocal laser endomicroscopy Follicular lymphoma arising in the duodenum is a distinct, relatively rare disease [1,2]. Here, we report our experience with confocal laser endomicroscopy (CLE) for follicular lymphoma of the duodenum with the corresponding histopathologic images, which, to our knowledge, is the first description of this. The patient was a 70-year-old woman in whom multiple s...

When Policy Topic is covered The use of the Afirma Gene Expression Classifier in fine needle aspirates of the thyroid that are cytologically considered to be indeterminate (follicular lesion of undetermined significance or follicular neoplasm) may be considered medically necessary in patients who have the following characteristics:  Thyroid nodules without strong clinical or radiologic finding...

Primary follicular mucinosis is a rare dermatosis characterized by the accumulation of mucin in the follicular epithelium and sebaceous glands. Clinically, it is characterized by the presence of papules or well-circumscribed and infiltrated plaques. In this paper, we report the case of a female patient, seven years old, evolving for three months with an asymptomatic, erythematous and infiltrate...

Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation. The most common form is a solitary lesion, but it can be multiple or eruptive, then called infundibulomatose. This case report illustrates a patient with m...