Development of a functional neuronal network during embryogenesis begins with pioneer axons creating a scaffold along which later-outgrowing axons extend. The molecular mechanism used by these follower axons to navigate along pre-existing axons remains poorly understood. We isolated loss-of-function alleles of fmi-1, which caused strong axon navigation defects of pioneer and follower axons in t...

This paper presents a generic interface which enables exploiting the multi-physics modeling capabilities of Modelica within the virtual test drive simulator CarMaker [1] using the Functional Mock-up Interface (FMI) [2]. Applications ranging from detailed studies of vehicle properties to hardware in the loop test-rigs require models of different complexity. CarMaker is provided an interface whic...

This article provides an overview of the development and implementation of a management development strategy for the South Western Sydney Area Health Service (SWSAHS). The program, the Frontline Management Initiative (FMI), was introduced as a developmental tool which enabled managers to identify those competencies that they already possess and those which they need to develop. The FMI will be ...

BACKGROUND It has been well documented that obesity is closely associated with metabolic syndrome (MetS). Although body mass index (BMI) is the most frequently used method to assess overweightness and obesity, this method has been criticized because BMI does not always reflect true body fatness, which may be better evaluated by assessment of body fat and fat-free mass. The objective of this stu...

High body fat is related to metabolic syndrome (MetS) in all ethnic groups. Based on the International Diabetes Federation (IDF) definition of MetS, the aim of this study was to explore thresholds of body fat percentage (BF%) and fat mass index (FMI) for the prediction of MetS among Colombian University students. A cross-sectional study was conducted on 1687 volunteers (63.4% women, mean age = ...

BACKGROUND Research indicates that plasma 25-hydroxyvitamin D [25(OH)D] is associated with insulin resistance, but whether regional adiposity confounds this association is unclear. OBJECTIVE This study assessed the potential influence of adiposity and its anatomical distribution on the relation between plasma 25(OH)D and insulin resistance. METHODS A secondary analysis of data from middle-a...

We aim to explore the independent associations of sedentary behaviors (SB) with body mass distribution among Chinese children. Data on the screen-based sedentary time (television viewing and computer use) and doing homework, physical activities and dietary intake of 1586 Chinese children (50.3% girls) aged 7-15 years were obtained through validated questionnaires. Skin-fold thickness, body heig...

The aviation industry stands to benefit from the technological advances that have come to be known as soft computing. This paper describes how soft computing techniques are being used to improve a pilot’s situational awareness. Of particular interest is the ability of a computer to add value to the raw sensor data, autonomously monitoring the aircraft’s situation for possible anomalies in fligh...

We examined the relationship between body fat and body mass index (BMI) in a multiethnic population of obese children. BMI z-scores were compared to DEXA measures of whole body composition and regional fat distribution. Fat mass index (FMI) was best predicted by the equation: 1/[(0.159- 0.013 x percentile of total abdominal fat)- (0.01 x BMI z-score)], where percentile of abdominal fat ranges f...

With the advent of the Functional Mock-up Interface (FMI) standard, exchanging dynamic models between modeling and simulation tools has been greatly simplified. At the core of it, FMI is a standardized and unified model execution interface for dynamic models. FMI has gained widespread adoption among users and numerous commercial and open source tools implement support for the standard. In this ...