Foot and mouth disease (FMD) is a contagious animal disease that causes irreparable damage to the economy of countries, including Iran in which this disease is a native one. Among the ways to combat FMD are vaccination and slaughter. Due to the specific situation of Iran, it is not possible to kill infected animals. Therefore, vaccination is the most important way to fight this disease. S...

Several protocols were developed and evaluated for the capture of foot-and-mouth disease (FMD) virus antigen on a microtitre plate to enable RNA extraction and reverse transcription to be carried out in the plate wells prior to PCR amplification of the cDNA product. One protocol enabled the FMD viral antigen from suspensions of clinical samples to be captured in the well by coating with a cockt...

Indonesia has been hit by outbreak of foot and mouth disease (FMD) after more than 30 years being free FMD. This study aimed to determine the level transmission FMD virus potential economic losses due outbreak. The method used in this research was a case which data for analysis secondary data. analytical reproduction number (R0) impact using Rushton Knight formula. results showed that rate R0 =...

The factors leading to persistent infection of foot-and-mouth disease (FMD) virus in ruminants are not well defined. This paper provides evidence of the presence of interleukin-10 (IL-10) early in the course of infection (1-4 days) as a factor in the development of persistence of FMD virus in cattle. Results showed that serum IL-10 in carrier cattle infected with FMD virus type O (n = 4) was de...

foot and mouth disease (fmd) is a highly contagious viral disease of ruminant which causes fever and postule on mouth, hoof and teat. the main purpose of this study was to determine and charachtrize isolated fmd virus from iran between 2005 - 2006, and to compare it with vaccine virus strains. after preparation of samples, serological test for typing of virus was performed. in order to virus is...

BACKGROUND Foot-and-mouth disease (FMD) is an economically important and highly contagious viral disease that affects cloven-hoofed domestic and wild animals. Virus isolation and enzyme-linked immunosorbent assay (ELISA) are the gold standard tests for diagnosis of FMD. As these methods are time consuming, assays based on viral nucleic acid amplification have been developed. RESULTS A previou...

Sporadic outbreaks of foot-and-mouth disease (FMD) have occurred in Libya for almost fifty years. During the spring of 2013, a countrywide serosurvey was undertaken to assess the level of FMD virus circulation and identify FMD virus serotypes in the country. A total of 4221 sera were collected, comprising samples from large ruminants (LR; n=1428 samples from 357 farms) and small ruminants (SR; ...

Foot and mouth disease (FMD) is the major disease constraint on international trade in livestock and their products. In the state of West Bengal, India, 1,082 FMD outbreaks were reported in the 18 years from 1985 to 2002. Of the prevalent four serotypes, O type FMD virus accounted for the most outbreaks (67%), followed by Asia-1 virus type (15%) and A virus type (14%). Outbreaks of the type C F...

Although New Zealand has never had a case of foot-and-mouth disease (FMD), the threat that this disease poses to the economy of this country has long been recognised. The unprecedented global spread of FMD caused by the type-O PanAsia strain, culminating in the outbreak that occurred in the United Kingdom in early 2001, has refocussed the concerns of biosecurity agencies worldwide. The 3 lines ...

Two interferon-inducing polycarboxylates were tested for antiviral activity on foot-and-mouth disease (FMD) virus infections in mice, guinea pigs, and swine. Polyacrylic acid, given intraperitoneally, had a protective effect on infection by FMD virus administered in the peritoneal cavity of mice and in the foot pad of guinea pigs. Chlorite-oxidized oxyamylose (COAM) was effective in mice at a d...