Mitochondria in a live HepG2 cell were visualized with a fluorescent probe to specify their location and state in a living cell. Then, mitochondria were selectively captured with a nanospray tip under fluorescence microscope, and thousands of small molecular peaks were revealed and unique steroids specific to mitochondria were also found. This fluorescence imaging combined with live single-cell...

A simple 4-hydroxynaphthalimide-derived colorimetric and ratiometric fluorescent probe (1) containing a receptor of levulinate moiety was designed and synthesized to monitor sulfite. Probe 1 could quantificationally detect sulfite by a ratiometric fluorescence spectroscopy method with high selectivity and sensitivity. Specially, probe 1 exhibited a 100 nm red-shifted absorption spectrum along w...

Although real-time label-free fluorescent aptasensors based on nanomaterials are increasingly recognized as a useful strategy for the detection of target biomolecules with high fidelity, the lack of an imaging-based quantitative measurement platform limits their implementation with biological samples. Here we introduce an ensemble strategy for a real-time label-free fluorescent graphene (Gr) ap...

Waste materials from mining tailings, often contain significant amounts of potentially valuable minerals. This study aimed at unearthing the minerals in Ijero Ekiti mine tailings. The tailing samples were randomly collected five locations area. analyzed for selected physico-chemical parameters: pH values, electrical conductivity, chloride, organic matter and X-Ray Fluorescence Spectrometry (XRF...

Fluorescence quenching spectrometry was applied to study the interactions between gold colloidal nanoparticles and alpha-fetoprotein (AFP). Experimental results show that the gold nanoparticles can quench the fluorescence emission of adsorbed AFP effectively. Furthermore, the intensity of fluorescence emission peak decreases monotonously with the increasing gold nanoparticles content. A mechani...

This review highlights the considerable advances in the chemical imaging of human fingermarks that provide more chemical information, including numerous endogenous and exogenous constituents. Despite remarkable development in DNA analysis and recognition, human fingermark analysis remains one of the priority approaches available for obtaining reliable forensic evidence. Additional information a...