The onset of this erythema in response to different times of exposure corresponds closely to that in the haired animal. Orally administered phenylbutazone (30 mg/kg) or subcutaneously administered fluocinolone acetonide (10 mg/kg) have an equivalent antierythemic effect on haired and hairless animals. The hairless rat may therefore be an attractive alternative to its haired counterpart in this ...

We intended to develop a desired ointment base suitable for treatment of bedsores including the proliferation of granulation and epidermis. The main bedsore bacteria detected in our hospital were S. aureus in gram-positive coccus and P. aeruginosa in gram-negative bacillus. As the macrogol ointment (MO) was found to have bactericidal effects on these bacteria, MO was adopted as the base for the...

The wound healing activity of ethanol extract of Terminalia bellirica Roxb. fruit was evaluated on excision and incision wound model, in albino rats, in the form of an ointment with two concentrations (2 and 4% w/w ointment) of fruit extract in simple ointment base. Both concentrations of the ethanol extract showed significant response in both the wound types tested when compared with the contr...

Spider web is being used in India and other countries to promote wound healing. Its ointment at 2.5 and 5% w/w concentrations was tested for wound healing activity in excision and incision wound models in rats. A significant reduction in the area of excision wound was observed for both the treatments when compared to normal healing and control ointment treatments. The period of epithelization f...

Adult and pediatric patients (n = 347) with atopic dermatitis enrolled in three multicenter, randomized, 6-week studies who had previously used steroids were analyzed to examine the null hypothesis that improvement in atopic dermatitis initiated after prior treatment with steroids eliminates any subsequent treatment differences between tacrolimus ointment and pimecrolimus cream. Of these patien...

BACKGROUND To compare the safety and efficacy of loteprednol etabonate ophthalmic ointment 0.5% (LE ointment), a new topical ointment formulation, with vehicle for the treatment of inflammation and pain following cataract surgery. METHODS Two randomized, multicenter, double-masked, parallel-group, vehicle-controlled studies were conducted. Patients aged ≥18 years with a combined postoperative...

The response was assessed subjectively, and by strength of grip and ring size measurements. The strength of grip in each hand was measured in the usual way by squeezing a small rubber bag attached to a sphygmomanometer and taking the average of three observations. Ring sizes were measured over the finger proximal interphalangeal joints using a set of standard jeweller's rings with half sizes. (...

A 60% (W/W) simple ointment of Udumbar (Ficus glomeruta) was prepared. The cases of cervical erosion were selected from S.S. Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi. The ointment was applied in the form of tampon following electric cauterization and compared the results with the triples sulpha ointment. It showed 95% cure rate as against 85% of Triple sulpha ...