BACKGROUND Fasciola spp. liver fluke cause pernicious disease in humans and animals. Whilst current control is unsustainable due to anthelmintic resistance, gene silencing (RNA interference, RNAi) has the potential to contribute to functional validation of new therapeutic targets. The susceptibility of juvenile Fasciola hepatica to double stranded (ds)RNA-induced RNAi has been reported. To expl...

Liver fluke infection caused by O. viverrini remains a major public health problem in many parts of Southeast Asia including Thailand, Lao PDR, Vietnam and Cambodia (IARC, 1994; Kaewpitoon et al., 2008b; Sripa et al., 2010; Sitthithaworn et al., 2012; Kaewpitoon et al., 2015a). Infection is acquired by ingestion of undercooked cyprinoid’s fish harboring infective metacercariae (Kaewkes 2003). L...

of hepatic aflatoxIn Bi and N-nitrosodiethylamine in infected males and 20-40% in infected females (Kirby et al., 1994). Immunohistochemical analysis of aflatoxIn Bi-DNA adducts in parasitized animaIs indicated that the greatest numbers of adducts occurred in the regions of highest CYP2A activity. Studies with a related liver fluke, Fasciola hepatica, also showed enhanced cyochrome P450-related...

Paleopathologists have begun exploring the pathoecology of parasitic diseases in relation to diet and environment. We are summarizing the parasitological findings from a mummy in the site of Lapa do Boquete, a Brazilian cave in the state of Minas Gerais. These findings in context of the archaeology of the site provided insights into the pathoecology of disease transmission in cave and rockshelt...

The aim of this action research was to enhance people's potential to prevent and control liver fluke infestation. The subjects were a total of 96 participants comprising 20 community leaders, 74 individuals handling and preparing food, and 2 officials from the Local Administration. Quantitative data were collected through questionnaire and the results of stool examination of the participants we...

Opisthorchiasis is a health problem in rural communities of Thailand, particularly in the northeast and north regions. Therefore, this study aimed to investigate raw fish consuming behavior related to liver fluke infection among the population at risk for opisthorchiasis and cholangiocarcinoma (CCA). A cross-sectional descriptive study was conducted in Meuang Yang district, Nakhon Ratchasima pr...

UNLABELLED Liver fluke Parafasciolopsis fasciolaemorpha is a parasite typical of elk (Alces alces). The present study describes the identification of a massive invasion of the liver fluke P. fasciolaemorpha in an elk in the Sobibór Landscape Park, Eastern Poland. In February 2016, samples of liver and faeces were collected from the elk during postmorte examination. A section of liver tissue and...

Until the late 1980’s electrical calibration systems used to compare primary and secondary voltages and resistance standards consisted of several different components. Systems like the Fluke 7105A and the Datron 4900 were the backbone of the majority of electrical calibration laboratories the world over. These systems were specifically combined to provide a traceable source, according to a set ...

Opisthorchiasis is a health problem in Thailand particularly in northeast and north regions where have been reported the highest of cholangiocarcinoma. Active surveillance is required, therefore a cross-sectional surveyed was conducted in Nong Bunnak sub-district of Nakhon Ratchasima province, Thailand. A total of 367 participants were selected by multistage sampling from 5 villages located nea...