An infusion pump powered by body heat is investigated in this paper, with the goal of addressing the needs of dermal wound healing. The infusion pump incorporates a Knudsen gas pump, a type of thermally driven pump, to pneumatic push the pharmaceutical agent from a reservoir. Two designs are considered: an integrated pump and reservoir, and a design with cascaded pump and reservoir. Thermal mod...

This study involves CFD simulation of blood flow through a non-pulsatile, axial pump consisting of a complex multisectioned impeller with rotating and stationary components, and a stationary housing. We use a particlebased method, Smoothed Particle Hydrodynamics (SPH), to investigate the effects of varying the impeller blade pitch angle and the gap size between the rotor and housing. Regions of...

The Pulsatile Catheter (PUCA) pump, a left ventricular assist device, was tested during acute experiments in calves using asynchronous and ECG-synchronous assist modes. The aim of the study is to compare ECG-synchronous and asynchronous assist, and to find the optimal driving mode for the PUCA-pump with respect to left ventricular myocardial oxygen consumption (LV MVO2), pump flow, and coronary...

Clinically adequate implementation of physiological control of a rotary left ventricular assist device requires a sophisticated technique such as the recently proposed method based on the Frank-Starling mechanism. In this mechanism, the stroke volume of the heart increases in response to an increase in the volume of blood filling the left ventricle at the end of diastole. To emulate this proces...

The effect of blood hematocrit (HCT) on a noninvasive flow estimation algorithm was examined in a centrifugal implantable rotary blood pump (iRBP) used for ventricular assistance. An average flow estimator, based on three parameters, input electrical power, pump speed, and HCT, was developed. Data were collected in a mock loop under steady flow conditions for a variety of pump operating points ...

Measurements of the time-varying flow in a centrifugal blood pump operating as a left ventricular assist device (LVAD) are presented. This includes changes in both the pump flow rate as a function of the left ventricle contraction and the interaction of the rotating impeller and fixed exit volute. When operating with a pulsing ventricle, the flow rate through the LVAD varies from 0-11 L/min dur...

In this paper, performance of centrifugal pump as turbine (PAT) is investigated numerically. Three different specific speeds are considered and three pumps are designed using diagrams from catalogues and CFturbo V.9 software. Next, models are analyzed by Ansys CFX 16 software and results are compared with those of CFturbo software. Also, a mesh study analysis for one case is performed in order ...

An estimator identifying the flow rate through a rotary blood pump was developed. This estimation algorithm uses the pump current and speed signals to estimate the blood flow rate through the pump. The algorithm was derived based on the force balance between the electric torque generated by the motor and the load torque, including the mechanical losses. The corresponding estimator parameters we...

Continuous-flow left ventricular assist devices (CF-LVADs) generally operate at a constant speed, which reduces pulsatility in the arteries and may lead to complications such as functional changes in the vascular system, gastrointestinal bleeding, or both. The purpose of this study is to increase the arterial pulse pressure and pulsatility by controlling the CF-LVAD flow rate. A MicroMed DeBake...