Extracellular signal-regulated kinase (ERK)-2 is presumed to play an important role in the development of post-traumatic joint contractures. Using a rat injury model, we investigated whether treatment with ERK2 small interfering RNA (siRNA) could reduce the extent of joint capsule fibrosis after an induced injury. Rats were separated into three groups (n = 32 each): non-operated control group, ...

Contracture of the iliotibial band leading to flexion and abduction deformity at the hip is common in residual paralysis after polio. Ober's test has been used to detect this, but it is unreliable and cannot determine the degree of contracture. We describe a new test which quantifies this contracture and can be used for comparative purposes.

Contracture of the elbow represents a disabling condition that can impair a person's quality of life. Regardless of the event that causes an elbow contracture, the conservative or surgical treatment is usually considered technically difficult and associated with complications. When the conservative treatment fails to restore an acceptable range of motion in the elbow, open techniques have been ...

Introduction: Improving the postoperative knee motion in total knee arthroplasty (TKA) has become a major goal for orthopaedic surgeons and joint prosthesis. The effect of the implant posterior condylar offset has recently generated much enthusiasm among researchers. [1] Some reports were concerned about the relationship between the posterior condylar offset and an extension gap. However, the p...

BACKGROUND: Stiffness is a common problem after knee arthroplasty and need for further procedure. Patients who experience this usually have poor outcome. Flexion contracture the most reported case in reports; however, we rare of patient with extension total (TKA).
 CASE REPORT: A 62-year-old woman was presented 3-month history right TKA. After 3 month she came to hospital complained that c...

BACKGROUND Severe knee flexion contractures greater than 80° are rare and challenging to manage. Previous studies have demonstrated unsatisfactory clinical results after correcting these deformities because residual flexion contractures were not corrected within a short period of time. We herein report the case of a patient with adult-onset Still's disease with 90° of bilateral knee flexion con...

introduction h syndrome (omim 612391) is an autosomal recessive disease with some features such as hyperpigmentation, hypertrichosis, heart anomalies, hepatosplenomegaly, hearing deficit, hypogonadism, short stature, flexion contracture of fingers and toes and hypertriglyceridemia. case presentation a 17-year-old boy with hyperpigmented, hypertrichotic and indurated seborrheic keratosis-like cu...

Camptodactyly is a permanent flexion contracture of the fingers at the proximal interphalangeal joints which may be familial or sporadic (Landouzy, I906; Gates, 1946). In practically all instances it affects the little finger. In addition the ring, middle, and index fingers may be involved. It is usually bilateral. Although there is no limitation to further flexion of the fingers, complete exte...

We report the results of a prospective study of the surgical release of 45 knee flexion contractures in 28 patients with myelomeningocele. The neurosegmental level was thoracic in ten patients, L1/2 in one, L3/4 in 11, and L5/S1 in six. In walkers the indication for surgery was a fixed flexion contracture impeding walking, and in non-walking patients it was a flexion contracture impeding transf...

Objectives: Flexion contracture in fingers of hands is a complication of Dupuytren's contracture and cannot be stopped by the progressive course. The aim of this study was to review the effect of splinting in corrective of contracture after Dupuytren's contracture surgery. Methods: To carry out this research, a kind of systematic evidence-based review process (Duffy 2005) was used. For data...