Fragile histidine triad (FHIT) serves a critical function as a tumor suppressor that inhibits p53 degradation by mouse double minute 2 (MDM2). The functional domains of FHIT involved in tumor inhibition was interpreted. In-silico screening data were employed to construct truncated forms of FHIT to assess their cytotoxic effects on the HT1080 cell line. Full FHIT expression was confirmed by west...

With the rapid development of society, growing interest in flexible electronics has led to remarkable progress recent advances manufacture [...]

Estimation of flexible functional forms for large consumer or producer demand systems is often precluded due to computational difficulties or due to a lack of degrees of freedom. We propose the concept of a semiflexible form, which is a special case of a flexible form but which requires fewer free parameters. Our proposed method of estimation allows the researcher to choose the degree of flexib...

The dimeric protein L7/L12 from bacterial ribosomes has a highly elongated and flexible structure. We have, using 1H NMR methods, analyzed the extent of the flexible region and also the size of the organized structures of the molecule. A number of mutants of the protein as well as monomeric and dimeric forms of the protein and a COOH-terminal fragment have been used for the identification of ce...

Two functional equations are considered that are motivated by three considerations: work in utility theory and psychophysics, questions concerning when pairs of degree 1 homogeneous functions can be homomorphic and calculating their homomorphisms, and the link of the latter questions to quasilinear mean values. The first equation is h(σ(y)x + [1 - σ(y)]y) = τ(y)h(x) + [1 - τ(y)]h(y) (x ≥ y ≥ 0)...

Abstract Nanotechnology and nanomaterials have offered sustainable design options for the built environment enabled architects to more flexible architectural forms. Carbon nanotubes excellent mechanical, electrical, thermal, chemical properties are useful in a wide range of engineering applications. However, role carbon nanotube composites as functional construction material has large potential...

A vexing challenge when using the utility-maximization framework to estimate consumers’ decisions on which set of goods to purchase and how much quantity to buy, is obtaining a functional form of the utility that satisfies three criteria: tractability, flexibility and global-regularity. Flexibility refers to the ability of utility function to impose minimal prior restrictions on demand elastici...

Textiles are having evolution from being normal protective clothing to smart and technical textiles. Electrically conducting fabrics forms the backbone of The textile combines electronics with structures, referred as “textronics”. One major challenge success such wearable resides in development lightweight flexible components, fibrous structures high electrical conductivity able withstand stres...