This prospective randomized study compares the long term results between total knee arthroplasty with a mobile bearing high flex and a fixed bearing posterior stabilized knee (LPS) in 39 patients. The Hospital for Special Surgery score (HSS) was calculated and radiographs in AP and lateral view were analyzed after a minimum follow-up of 10 years. No significant differences between the two group...

PURPOSE To characterize the clinical profile of femtosecond lenticule extraction (FLEx) correlated with ultrastructural analysis of the corneal interface and in vivo real-time intraocular pressure (IOP). METHODS Prospective clinical case series with experimental studies; consecutive patients underwent FLEx at a single tertiary center over 10 months with postsurgical follow-up of 3 months. The...

PURPOSE The purpose of this study was to compare postoperative range of motion and functional outcomes among patients who received high-flexion total knee arthroplasty using cruciate-retaining (CR-Flex) and posterior-stabilized (PS-Flex) type prostheses. MATERIALS AND METHODS Among 127 patients (186 knees) who underwent high-flexion total knee arthroplasty between 2005 and 2007, 92 knees were...

STUDY OBJECTIVES To compare adherence and clinical outcomes between flexible positive airway pressure (PAP) [C-Flex; Respironics; Murraysville, PA] and standard PAP therapy (ie, continuous positive airway pressure [CPAP]). DESIGN AND SETTING A controlled clinical trial of CPAP therapy vs therapy using the C-Flex device in participants with moderate-to-severe obstructive sleep apnea. Participa...

INTRODUCTION Accelerometers are commonly used to assess physical activity. Consumer activity trackers have become increasingly popular today, such as the Fitbit. This study aimed to compare the average number of steps per day using the wrist-worn Fitbit Flex and waist-worn ActiGraph (wGT3X-BT) in free-living conditions. METHODS 104 adult participants (n = 35 males; n = 69 females) were asked ...

The radial flex (R-flex) circuit (previously part no. 18596-60038) has been redesigned and is now available as part no. 18596-60915. This new circuit requires a modified turret (still part no. 18596-60515). “B” trays (18596B) with serial numbers greater than 3032A22099 have the modified turret; therefore, when replacing R-flex circuits on trays with serial numbers below this, check the turret a...

BACKGROUND Whereas the effects of various inspiratory ventilatory modifications in lung injury have extensively been studied, those of expiratory ventilatory modifications are less well known. We hypothesized that the newly developed flow-controlled expiration (FLEX) mode provides a means of attenuating experimental lung injury. METHODS Experimental acute respiratory distress syndrome was ind...

Physically-based atmospheric correction of optical Earth Observation satellite data is used to accurately derive surface biogeophysical parameters free from the atmospheric influence. While water vapor or surface pressure can be univocally characterized, the compensation of aerosol radiometric effects relies on assumptions and parametric approximations of their properties. To determine the vali...

Mammalian cell-based bioprocesses are used extensively for production of therapeutic proteins. Off-line monitoring of such cultivations via manual sampling is often labor-intensive and can introduce operator-dependent error into the process. An integrated multi-functional off-line analyzer, the BioProfile FLEX (NOVA Biomedical, Waltham MA) has been developed, which combines the functionality of...

MOTIVATION Identification of flexible regions of protein structures is important for understanding of their biological functions. Recently, we have developed a fast approach for predicting protein structure fluctuations from a single protein model: the CABS-flex. CABS-flex was shown to be an efficient alternative to conventional all-atom molecular dynamics (MD). In this work, we evaluate CABS-f...