Flavones are important copigments found in the flowers of many higher plants and play a variety of roles in plant adaptation to stress. In Medicago species, flavones also act as signal molecules during symbiotic interaction with the diazotropic bacterium Sinorhizobium meliloti. They are the most potent nod gene inducers found in root exudates. However, flavone synthase II (FNS II), the key enzy...

Flavonoids are widely occurring in our diet. In this study, the effects of nine flavonoids on acetaminophen (APAP) oxidation and related cytochrome P450 (P450) enzyme activities were investigated. With rat liver microsomes, APAP oxidation was stimulated 2- to 4-fold by 50 microM flavone or tangeretin and inhibited 65% by myricetin or quercetin. Only a slight inhibition of APAP oxidation was cau...

Flavone, dextrose and long swim stress exhibited antinociception. Degree of antinociception was greater with long swim stress as compared to flavone or dextrose. Combination of these treatments resulted in potentiation of antinociception. Naloxone (opioid antagonist; 5 mg/kg i.p.) antagonised flavone or long stress induced antinociception showing opioid medicated mechanism, however, failed to r...

Flavonoids are secondary metabolites derived from phenylalanine and acetate metabolism. They fulfil a variety of functions in plants and have health benefits for humans. During the synthesis of the tricyclic flavonoid natural products in plants, oxidative modifications to the central C ring are catalyzed by four of FeII and 2-oxoglutarate dependent (2-ODD) oxygenases, namely flavone synthase I ...

Knowledge of the inheritance of C-glycosyl flavone synthesis in maize (Zea mays L.) silk tissues has been acquired through detailed genetic studies involving primarily germplasm from the Corn Belt Dent race. To test the robustness of this genetic knowledge, we examined C-glycosyl flavone synthesis in a genetically distinct germplasm pool, popcorn. C-glycosyl flavone profiles and levels and the ...

Z. Naturforsch. 50c, 345-352 (1995); received January 27/February 20, 1995 Liverworts, Frullania, Flavone Aglycones, Acylated Flavone Glycosides, Chemotaxonomy From Frullania teneriffae 5 known flavone aglycones and 6 flavone glycosides were iso­ lated, among them the new 6-OH-luteolin-6-0-ß-D-glucoside-7-0-ß-D-glueoside-6'"-(3-hydroxy-3-methylglutaroylester). F. cesatiana contains 2 flavone-di...

The metabolism of flavone C-glucosides and p-coumaric acid from antioxidant of bamboo leaves (AOB) in rats is discussed systematically in the present study. Following single oral administration of AOB, p-coumaric acid was detected in plasma but not in gastrointestinal tract extracts and faeces, and the corresponding absorption pharmacokinetic curve at different time points showed a prolonged el...

Disruptions in whole-body lipid metabolism can lead to the onset of several pathologies such as nonalcoholic fatty liver disease (NAFLD) and cardiovascular diseases (CVDs). The present study aimed at elucidating the molecular mechanisms behind the lipid-lowering effects of the flavone luteolin-7-glucoside (L7G) which we previously showed to improve plasma lipid profile in rats. L7G is abundant ...

activity in vitro and in vivo. The several action mechanisms have been proposed to explain their in vivo anti-inflammatory activity. Many flavonoids exert anti-oxidative and free radical scavenging activities. Some derivatives modulate cellular activities of the inflammation-associated cells such as mast cells and lymphocytes. In particular, varieties of flavonoid derivatives including querceti...

Chinese wild rice (Zizania latifolia) is rich in phenolic compounds, particularly flavonoids. This study identified 203 basic helix-loop-helix (bHLHs) Z. latifolia and showed that ZlbHLH196 (Zla16G011250) corresponds to the ZlRc gene latifolia, with its protein product localizing nucleus. Notably, pericarps of ZlRc-overexpressing (OE) are brown, whereas those wild-type (WT) nonpigmented. The to...