objective: long-term retention of pit and fissure sealants is crucial for their success. this clinical study evaluated the retention rate of a flowable composite resin (filtek supreme xt flowable restorative) compared to a conventional resin-based sealant (concise light cure white sealant) over 12 months. materials and methods: forty subjects aged 6 to 9 years were included in the study. using ...

Coloboma is a congenital disease that contributes significantly to childhood blindness. It results from the failure in closing the optic fissure, a transient opening on the ventral side of the developing eye. Although human and mouse genetic studies have identified a number of genes associated with coloboma, the detailed cellular mechanisms underlying the optic fissure closure and coloboma form...

BACKGROUND AND OBJECTIVES Fluoride is being used for the prevention of dental caries since a long time. Incorporation of fluoride in pit and fissure sealants has been found to reduce initiation and progression of pit and fissure caries. Authors conducted this study to evaluate and compare the effect of fluoride releasing pit and fissure sealants on the inhibition of demineralization of adjacent...

Background: Nipple fissure is one of the most common diseases in breastfeeding which leads to maternal pain and disruption of the mother-infant relationship. Since the most important consequence of nipple fissure is the deprivation of the infant from breast milk, it is very important to prevent and treat this condition. The aim of this study was to investigate the effect of the topical form of ...