background: central nervous system malformations are the second most common congenital malformations after congenital heart diseases. these malformations are associated with many instances of morbidity and mortality which underline the importance of prevention and their early diagnosis. objective: the objective of this study is the diagnosis of neural tube defect (ntds) in the first trimester a...

The purpose of this study was to examine variations in endogenous oxytocin levels in pregnancy and postpartum state. We also explored the associations between delivery variables and oxytocin levels. A final sample of 272 mothers in their first trimester of pregnancy was included for the study. Blood samples were drawn during the first trimester and third trimester of pregnancy and at 8 weeks po...

abortion is an important problem in obstetrics throughout the world. the common and standard method for pregnancy termination at first trimester is surgery (curettage). nowadays, an effective method of pregnancy termination at first trimester is medical treatments. the aim of this study is to compare misoprostol alone or in combination with methotrexate for pregnancy termination at first trimes...

Vaginal bleeding is the most common cause of presentation to the emergency department in the first trimester. Approximately half of patients with first trimester vaginal bleeding will lose the pregnancy. Clinical assessment is difficult, and sonography is necessary to determine if a normal fetus is present and alive and to exclude other causes of bleeding (eg, ectopic or molar pregnancy). Diagn...

Background: Early diagnosis of gestational diabetes is one of the most important applications of taking care of during pregnancy. The current study was done to find the correlation between hemotocrit in the first trimester of pregnancy with gestational diabetes in women who referred to Milad Hospital in Tehran in 2009-2010. Materials and Methods: A prospective cohort study was conducted on 700 ...

BACKGROUND Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes such as preeclampsia and macrosomia. Women with polycystic ovary syndrome (PCOS) are at increased risk of developing GDM. Today, GDM is diagnosed by oral glucose tolerance test (OGTT), a rather cumbersome test for the women and health care system. The objectives of this study were to investigate whether...

Background: Preeclampsia is the most important problems in pregnancy that irreparable complications for mother and fetus has. Maternal body mass index in the first trimester of pregnancy and weight gain during pregnancy is important in pregnancy outcome. This study to determine the association BMI first trimester mothers with preeclampsia have been done Materials and Methods: In this prospectiv...

BACKGROUND First trimester Pregnancy Associated Plasma Protein A (PAPP-A) levels, routinely measured for aneuploidy screening, may predict development of preeclampsia. This study tests the hypothesis that first trimester PAPP-A levels correlate with soluble fms-like tyrosine kinase-1 (sFlt-1) levels, an angiogenic marker associated with preeclampsia, throughout pregnancy. METHODS sFlt-1 level...

background: measuring of maternal serum pregnancy-associated plasma protein-a (papp-a) in first trimester can be a way for early detection of adverse prenatal outcome due to faulty placenta.objective: the aim was to determination of association between placental thickness in second trimester with low level of papp-a in first trimester.materials and methods: in this cohort study, serum papp-a of...

Abortion is an important problem in obstetrics throughout the world. The common and standard method for pregnancy termination at first trimester is surgery (curettage). Nowadays, an effective method of pregnancy termination at first trimester is medical treatments. The aim of this study is to compare misoprostol alone or in combination with methotrexate for pregnancy termination at first trimes...